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Now showing items 1-20 of 34

    • Automated aberration correction for STED microscopy 

      Ghosh, Debadrita (2023-09-26)
      Stimulated emission depletion (STED) microscopy is a powerful super resolution fluorescence microscopy technique that surpasses the diffraction limit. However, the performance of a STED microscope can be adversely ...
    • Dynamical remodeling of visual circuit architecture 

      Wu, Wenqi (2023-06-14)
      Visual cortex, as a model for plasticity, has been studied for many years. It is still controversial, however which mechanisms guide the emergence and development of a hallmark of the cortical functional architecture, ...
    • Towards an active matter perspective on sarcomere dynamics in cardiomyocytes 

      Härtter, Daniel (2023-04-19)
      The contraction of cardiac muscles emerges from the collective dynamics of myosin motor proteins organized in sarcomeres, 2 μm-sized contractile units. Inside individual cardiomyocytes, dozens of sarcomeres in series form ...
    • High-Resolution Reflection Microscopy via Absorbance Modulation 

      Jain, Parul (2023-01-11)
      The properties of composite materials are primarily governed by their microstructural features, which can vary in size from a few nanometres to several micrometres. Optical microscopy is one of the primary tools for ...
    • Advanced multiplexing techniques in single molecule localisation microscopy 

      Oleksiievets, Nazar (2022-05-13)
      DNA point accumulation for imaging in nanoscale topography (DNA-PAINT) is a powerful super-resolution technique highly suitable for multi-target (multiplexing) bio-imaging applications. However, multiplexed imaging of cells ...
    • Anomalous Diffusion in Protein Dynamics 

      Volkhardt, Andreas (2022-02-14)
      Almost all processes in life are governed by proteins which are biomolecules consisting of a chain of amino acids. They perform a wide range of functions in organisms, including catalysis of metabolic reactions, transport ...
    • Fast, Three-Dimensional Fluorescence Imaging of Living Cells 

      Jang, Hongje (2022-01-21)
      This thesis focuses on multi-plane fluorescence microscopy for fast live-cell imaging. To improve the performance of multi-plane microscopy, I developed new image analysis methods. I used these methods to measure and analyze ...
    • New Concepts for STED Microscopy 

      Kratz, Julia (2022-01-04)
      Fluorescence nanoscopy allows to non-invasively resolve three-dimensional cellular structures beyond the diffraction limit. One of these high resolution imaging techniques is stimulated emission depletion (STED) microscopy. ...
    • Optogenetic Control of Cardiac Arrhythmias 

      Hussaini, Sayedeh (2022-01-04)
      The regular, coordinated contraction of the heart muscle is orchestrated by periodic waves generated by the heart’s natural pacemaker and transmitted through the heart’s electrical conduction system. Abnormalities occurring ...
    • Akustische Strömung in Wasser durch Ultraschall im UHF-Bereich 

      Eisener, Julian (2021-06-07)
      The goal of this predominantly experimental work is the understanding and investigation of acoustic streaming, which is generated by the sound field of new type of a very high frequency transducers. The transducers have ...
    • Variational Approaches to Free Energy Calculations 

      Reinhardt, Martin (2021-01-21)
      Gradients in free energy are the driving forces of thermodynamic systems. Knowledge thereof thus enables a first-principles understanding of condensed-phase many-body systems such as macromolecular assemblies, colloids or ...
    • Ratiometric fluorescence imaging and marker-free motion tracking of Langendorff perfused beating rabbit hearts 

      Kappadan, Vineesh (2021-01-06)
      Optical mapping is a fluorescence based imaging technique used extensively in cardiac research to study the electrophysiological properties of isolated hearts kept at physiological conditions. The major limitation of ...
    • Multi-parameter assessment of mechano-sensitivity driven differentiation of human mesenchymal stem cells 

      Hauke, Lara (2020-12-22)
      What factors and conditions control stem cell differentiation is currently one of the major questions in biomedical research. What factors ultimately influence the cells’ decision is unclear but it has been shown, that ...
    • Towards validation and map quality assessment in electron cryo-microscopy 

      Fiedler, Sabrina (2020-09-10)
      Structural biology is the study of the assembly of proteins and protein complexes. These proteins and protein complexes are small units in the cell of a living being. In order to sustain life they take care of biochemical ...
    • Neutrophil Extracellular Trap (NET) Formation: From Fundamental Biophysics to Delivery of Nanosensors 

      Meyer, Daniel (2020-04-21)
      Immune cells have remarkable properties. They are able to migrate long distances, cross dense cell barriers and use a wide range of tools to identify and fight foreign materials in our body. In this context, neutrophil ...
    • Ballistic electron transport in graphene nanodevices and billiards 

      Datseris, George (2019-10-17)
      Nanodevices are objects with broad relevance for today's society, which bases its economy, operation, and communication onto digital resources. In ballistic nanodevices, disorder has either negligible or minor impact on ...
    • Modeling electrodynamics in the vicinity of metal nanostructures 

      Ruhlandt, Daja Talina Helga Wilhelmine (2019-03-08)
      In this work, we show how a profound theoretical understanding of a seemingly exotic phenomenon, namely the influence of metal structures on fluorescence lifetimes, has lead to the development of a microscopy technique ...
    • Stereo 3D-SMS microscopy of large sample volume 

      Mittelstädt, Haugen (2018-12-20)
      The functionality of the human body and with it many of its diseases are based on single cells or even on single cellular components. It is therefore essential to gain insight into the intra- and intercellular processes ...
    • Time-resolved X-ray phase-contrast tomography 

      Ruhlandt, Aike (2018-06-27)
      X-ray tomography allows to obtain the three-dimensional (3d) structure of weakly interacting objects, such as tissue samples in biomedical imaging or nanoscale structures in materials science, with high spatial resolution. ...
    • Kinetics of structure formation in block copolymers 

      Ren, Yongzhi (2018-04-25)
      Block copolymers are amphiphilic macromolecules, which consist of multiple incompatible parts. Although block copolymers may differ in their microscopic interactions, their phase behaviors share many similarities. In ...