Positive Familienanamnese bezüglich eines Myokardinfarkts und ihr Effekt auf ausgewählte Faktoren der gesundheitsbezogenen Lebensqualität - Ergebnisse der Diast-CHF-Studie

Pieper, Annekatrin

dc.contributor.advisor	Edelmann, Frank Prof. Dr.
dc.contributor.author	Pieper, Annekatrin
dc.date.accessioned	2020-09-23T14:08:27Z
dc.date.available	2020-10-06T22:50:03Z
dc.date.issued	2020-09-23
dc.identifier.uri	http://hdl.handle.net/21.11130/00-1735-0000-0005-148E-5
dc.identifier.uri	http://dx.doi.org/10.53846/goediss-8210
dc.identifier.uri	http://dx.doi.org/10.53846/goediss-8210
dc.language.iso	deu	de
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc	610	de
dc.title	Positive Familienanamnese bezüglich eines Myokardinfarkts und ihr Effekt auf ausgewählte Faktoren der gesundheitsbezogenen Lebensqualität - Ergebnisse der Diast-CHF-Studie	de
dc.type	doctoralThesis	de
dc.title.translated	Family history of myocardial infarction and their effect on selected factors of health related quality of life – Results of the Diast-CHF-study	de
dc.contributor.referee	Edelmann, Frank Prof. Dr.
dc.date.examination	2020-09-29
dc.description.abstracteng	The purpose of the present study was to determine whether patients with a family history of premature myocardial infarction were more often affected by psychosocial risk factors and furthermore have lower health related quality of life. In addition, this dissertation investigated the impact of a family history of premature myocardial infarction on selected end points such as overall mortality and cardiovascular hospitalisation. Therefor, a community of patients of the Diast-CHF-study (n= 1470) was examined and separated into two groups: Patients with (n = 187) or without (n= 1283) a family history of premature myocardial infarction. Somatic and psychosocial risk factors were collected and included in the analysis. The study group with a family history of premature myocardial infarction was significantly more often affected by vital exhaustion, anxiety, type D personality, negative attachment patterns, lower social support, used depressive coping to handle diseases and had a significantly lower health related quality of life. During an observation period of five years, we found no significant difference between both groups as to the endpoints own myocardial infarction, cardiovascular and overall mortality and cardiovascular hospitalisation. A direct influence of a family history could not be demonstrated within the five year period. However, we demostrate that vital exhaustion as a factor of health related quality of life elevates cardiovascular mortality and hospitalisation amongst other factors. Our observations suggest that not the family history of myocardial infarction itself, but their significant effect on increase of psychosocial risk factors in persons concerned leads to higher risk of cardiovascular mortality and hospitalisation.	de
dc.contributor.coReferee	Meyer, Thomas Prof. Dr.
dc.subject.ger	Myokardinfarkt	de
dc.subject.ger	Familienanamnese	de
dc.subject.ger	Diast-CHF-Studie	de
dc.subject.ger	gesundheitsbezogene Lebensqualität	de
dc.subject.ger	vitale Erschöpfung	de
dc.subject.eng	myocardial infarction	de
dc.subject.eng	family history	de
dc.subject.eng	Diast-CHF-study	de
dc.subject.eng	health related quality of life	de
dc.subject.eng	vital exhaustion	de
dc.identifier.urn	urn:nbn:de:gbv:7-21.11130/00-1735-0000-0005-148E-5-7
dc.affiliation.institute	Medizinische Fakultät	de
dc.subject.gokfull	Medizin (PPN619874732)	de
dc.description.embargoed	2020-10-06
dc.identifier.ppn	1733650881

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Human- und Zahnmedizin [2877]

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