Vergleich unterschiedlicher Methoden zur Evaluation des Kollateralisierungsstatus als Prädiktor für das Ergebnis nach Thrombektomie

Peter, Carolin

dc.contributor.advisor	Psychogios, Marios-Nikos Prof. Dr.
dc.contributor.author	Peter, Carolin
dc.date.accessioned	2021-08-10T09:51:40Z
dc.date.available	2021-08-23T00:50:03Z
dc.date.issued	2021-08-10
dc.identifier.uri	http://hdl.handle.net/21.11130/00-1735-0000-0008-58DA-0
dc.identifier.uri	http://dx.doi.org/10.53846/goediss-8777
dc.identifier.uri	http://dx.doi.org/10.53846/goediss-8777
dc.language.iso	deu	de
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc	610	de
dc.title	Vergleich unterschiedlicher Methoden zur Evaluation des Kollateralisierungsstatus als Prädiktor für das Ergebnis nach Thrombektomie	de
dc.type	doctoralThesis	de
dc.title.translated	Comparison of different methods for evaluating the collateral status as a predictor of outcome after thrombectomy	de
dc.contributor.referee	Liman, Jan Prof. Dr.
dc.date.examination	2021-08-17
dc.description.abstracteng	Collateral status is an important factor determining outcome in acute ischemic stroke. Hence, different collateral scoring systems have been introduced. We applied different scoring systems on single- and multi-phase computed tomography angiography and compared them to CT perfusion parameters to identify the best method for collateral evaluation in patients with acute ischemic stroke. A total of 102 patients with acute ischemic stroke due to large vessel occlusion in the anterior circulation who underwent multimodal CT imaging and who were treated endovascularly were included. Collateral status was assessed on spCTA and mpCTA using four different scoring systems and compared to CT perfusion parameters. Logistic regression was performed for predicting favorable outcome. All collateral scores correlated well with each other and with CT perfusion parameters. Comparison of collateral scores stratified by extent of perfusion deficit showed relevant differences between groups. A spCTA collateral score discriminated best between favorable and unfavorable outcome as determined using the modified Rankin Scale 3 months after stroke. Collateral status evaluated on spCTA may suffice for outcome prediction and decision making in acute ischemic stroke patients, potentially obviating further imaging modalities like mpCTA or CT perfusion.	de
dc.contributor.coReferee	Dressel, Ralf Prof. Dr.
dc.subject.eng	Acute stroke	de
dc.subject.eng	Collateral circulation	de
dc.subject.eng	Perfusion	de
dc.subject.eng	Computed tomography angiography	de
dc.subject.eng	Treatment outcome	de
dc.identifier.urn	urn:nbn:de:gbv:7-21.11130/00-1735-0000-0008-58DA-0-4
dc.affiliation.institute	Medizinische Fakultät	de
dc.subject.gokfull	Radiologie (PPN619875593)	de
dc.description.embargoed	2021-08-23
dc.identifier.ppn	1766080448

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Human- und Zahnmedizin [2881]

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