Expressionsanalyse chondrogener Progenitorzellen im ex-vivo Migrationsexperiment
Expression analysis of chondrogenic progenitor cells in ex-vivo migration experiment
von Gunar Joachim Wagner
Datum der mündl. Prüfung:2015-05-18
Erschienen:2015-04-30
Betreuer:Prof. Dr. Nicolai Miosge
Gutachter:Prof. Dr. Nicolai Miosge
Gutachter:PD Dr. Kaomei Guan-Schmidt
Dateien
Name:Dissertation_GW 5.pdf
Size:5.68Mb
Format:PDF
Zusammenfassung
Englisch
The chondrogenic progenitor cells are under control of the expression factors Sox9 and Runx2 favoritising either chondrogenic or osteogenic behavior. In this study we examine the impact on chondrogenic progenitor cells with a Runx2 knockdown. Using a migration experiment we could analyse the expression of collagen typ 1 and 2 of that cells.
Keywords: regenerative medicine