Roughly one hundred million years ago, solitary insect species evolved
social interactions that enabled the formation of colonies. A main reason for this
advance was their ability to feed each other with previously ...
At chemical synapses, synaptic vesicles, membrane-enclosed entities filled with neurotransmitters, undergo exocytosis at restricted areas of the presynaptic membrane called active zones (AZ). The core AZ proteins form a ...
Neuregulin 1 (NRG1) is the best characterized member of a family of epidermal growth factor (EGF)-like domain containing proteins that serve as ligands for tyrosine kinase receptors of the ErbB family. NRG1 and its main ...
Autism is known as a heritable neurodevelopmental disorder, diagnosed prior to the age of three years in humans based on three major domains: (1) impairment in social interaction (2) communication deficits (3) restricted ...
Neurotransmission requires the release of neurotransmitters from synaptic vesicles. This
occurs via fusion of the vesicle to the pre-synaptic membrane upon stimulation. However, not
all synaptic vesicles are equally ...