Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS), where myelin-reactive T cells play a key role in the inflammatory events responsible for the formation of demyelinated lesions. Auto-reactive ...
The pathogenic mechanisms and the origins of neurodegenerative diseases
remain unclear on molecular level. Increasing evidences postulate alterations in
miRNA signatures as critical factor in pathogenesis, progression ...
Myocardial infarction (MI), defined as heart damage due to prolonged ischemia, accounts for significant mortality and morbidity and has a substantial financial burden worldwide. While major advancements have been achieved ...
Reactive oxygen species (ROS) are highly reactive molecules produced in any biological system. When ROS are produced in higher amounts, they are lethal to cells. Therefore cells possess a tight redox regulation through ...
Multiple sclerosis is inflammatory central nervous system disease, characterised by areas of demyelination and axonal loss. The pathogenic mechanism behind the disease still remains unknown, however it is thought to be ...