Neutrophil granulocytes are the largest group of white blood cells and play a significant role
in the innate immune system. With the discovery of a vast number of thus far unknown
functions, neutrophil granulocytes became ...
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive solid tumors in humans. Median survival is around 12 months and is due to late diagnosis, early metastatic spread, and a high resistance towards available ...
In breast cancer patients, it is usually not the primary tumor that is the cause of death, but rather the development of locoregional or distant recurrence. Despite seemingly complete resection, some tumor cells often ...
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS), where myelin-reactive T cells play a key role in the inflammatory events responsible for the formation of demyelinated lesions. Auto-reactive ...
The pathogenic mechanisms and the origins of neurodegenerative diseases
remain unclear on molecular level. Increasing evidences postulate alterations in
miRNA signatures as critical factor in pathogenesis, progression ...