| dc.contributor.advisor | Rothenberger, Aribert Prof. Dr. | |
| dc.contributor.author | Schlieben, Anne Charlott | |
| dc.date.accessioned | 2014-08-12T08:13:09Z | |
| dc.date.available | 2014-09-08T22:50:07Z | |
| dc.date.issued | 2014-08-12 | |
| dc.identifier.uri | http://hdl.handle.net/11858/00-1735-0000-0022-5F4C-0 | |
| dc.identifier.uri | http://dx.doi.org/10.53846/goediss-4643 | |
| dc.language.iso | deu | de |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/ | |
| dc.subject.ddc | 610 | de |
| dc.title | Aspekte der Zeitverarbeitung bei Kindern mit Aufmerksamkeitsdefizit-Hyperaktivitätsstörung (ADHS) | de |
| dc.type | doctoralThesis | de |
| dc.title.translated | Aspects of time perception in children with ADHD | de |
| dc.contributor.referee | Antal, Andrea Prof. Dr. | |
| dc.date.examination | 2014-08-12 | |
| dc.description.abstracteng | Background: Detecting genetic factors involved in attention deficit hyperactivity disorder (ADHD) is complicated because of their small effect sizes and complex interactions. The endophenotype approach eases this coming closer to the relvant genes. Different aspects of temporal information processing are known to be affected in ADHD. Thus, some of these aspects could represent candidate endophenotype for ADHD. Method: Fifty-four sib-pairs with at least one child with ADHS and 40 control children aged 6-18 years were recruited and asked to perform two discrimination tasks, one with base duration of 50 ms on automatic timing and one with a base duration of 1000 ms on cognitively controlled timing. Results: Wereas children with ADHD, but not their unaffected siblings, were impaired in discrimination of longer intervals, both groups were impaired in discrimination brief intervals. Furthermore, a significant within-family correlation was found for dirscrimination of brief intervals. Task performances of subjects of the control group correlated with individual levels of hyperactivity/ impulsivity for discrimination of brief intervals, but not of longer intervalls. Conclusions: Cognitively controlled and also automatic processes of temporal information processing are impaired in children with ADHD. Discrimination of longer intervals appears as a typical disease marker whereas discrimination of brief intervals shows up as a vulnarability marker. Discrimination of brief intervals was found to be familial and linked to levels of hyperactivity/ impulsivity. Taken togehter, discrimination of brief intervals represents a candidate endophenotype of ADHD. | de |
| dc.contributor.coReferee | Oppermann, Martin Prof. Dr. | |
| dc.subject.ger | ADHS | de |
| dc.subject.ger | Zeitverarbeitung | de |
| dc.subject.ger | Zeitwahrnehmung | de |
| dc.subject.ger | Endophänotyp | de |
| dc.subject.eng | ADHD | de |
| dc.subject.eng | time perception | de |
| dc.subject.eng | duration discrimination | de |
| dc.subject.eng | endophenotype | de |
| dc.identifier.urn | urn:nbn:de:gbv:7-11858/00-1735-0000-0022-5F4C-0-0 | |
| dc.affiliation.institute | Medizinische Fakultät | de |
| dc.subject.gokfull | Psychiatrie (PPN619876344) | de |
| dc.description.embargoed | 2014-08-19 | |
| dc.identifier.ppn | 796514399 | |