Charakterisierung des Targetingverhaltens präsynaptischer Proteine

Characterization of the targeting of presynaptic proteins

by Donatus Riemann
Doctoral thesis
Date of Examination:2018-05-14
Date of issue:2018-04-24
Advisor:Prof. Dr. Thomas Dresbach
Referee:Prof. Dr. Silvio Rizzoli
Referee:Prof. Dr. Rainer Mausberg
Persistent Address: http://dx.doi.org/10.53846/goediss-6846

 

 

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Abstract

English

Studying features of proteins can be done by expressing recombinant versions of those proteins in a cellular environment which facilitates correct transport and distribution. Here this model was used to study features of recombinant versions of Bassoon, a structural component of active zones, RIBEYE, a protein involved in building ribbon synapses and Rogdi, a protein that had never been described in synapses before.
Keywords: Rogdi, Bassoon, RIBEYE; Mover; Neuron; Synapse; Hippocampus; Transfection; Recombinant
 
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