Blättern GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften nach "Rodnina, Marina Prof. Dr." Betreuer

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    • Release of a Natural mRNA During Recycling of the Prokaryotic Ribosome 

      Willmer, Moritz Willy Rudolf (2023-06-20)
      Ribosome recycling is the last step of the bacterial translation cycle. The release of the peptide leaves a 70S ribosome with a deacylated tRNA in the P site and the stop codon of the mRNA in the A site. The combined action ...

    • Ribosome dynamics during spontaneous frameshifting 

      Poulis, Panagiotis (2022-10-18)
      During protein synthesis, the ribosome moves along the mRNA in steps of three nucleotides at a time to maintain the translational reading frame. However, on some mRNA sequences that are denoted as slippery, ribosomes may ...

    • Ribosome Processivity and Co-translational Protein Folding 

      Thommen, Michael Sebastian (2017-04-21)
      Synthesis of polypeptide chains on the ribosome occurs at a non-uniform rate. mRNA sequences translated at a high rate are interspersed by segments that lead to translational pausing. The rate of translation elongation is ...

    • The Role of EF-G in Translational Reading Frame Maintenance on the Ribosome 

      Peng, Bee-Zen (2019-09-10)
      Translation of an mRNA by the ribosome is the final step of gene expression. During translation initiation, the ribosome establishes the mRNA reading frame with the help of initiator tRNA binding to the start codon. This ...