Cellular levels of RNA depend on the rate of its synthesis and degradation. While synthesis is
performed by RNA polymerase conserved in all domains of life, the enzymes responsible for RNA
degradation are more unique ...
Influenza A virus (IAV) increases morbidity and mortality rates and novel antivirals are needed to combat the virus. Errors of the viral polymerase lead to the generation of defective RNAs. These DI-RNAs may interfere with ...
Since its first use as a genetically encoded fluorescent marker in 1994, GFP and its
homologues have fundamentally revolutionized live-cell fluorescence imaging and
became an essential tool for biomedical research. Many ...
Aspergillus fumigatus is a globally distributed opportunistic filamentous fungal pathogen
mainly found in compost and represents the main cause of pulmonary aspergillosis in
immunocompromised individuals. Fungal development ...
Since its discovery about 40 years ago, the transcription factor p53 has turned into the most
extensively studied protein in the context of human cancers due to its essential role in
promoting tumor suppression. P53 ...