The goal of this study was to investigate how individuated finger movements are coded in area AIP, F5 and M1. At the single neuron level, most of the units in all three areas were “broadly tuned”, responding during multiple ...
Translation is a highly conserved molecular process during which the genetic information
stored in an mRNA molecule is translated into a polypeptide chain that eventually folds
into functional three-dimensional proteins. ...
Otoferlin is a large multi-C2 domain protein indispensable for hearing and synaptic transmission in auditory inner hair cells (IHCs). Mutations within the OTOF gene, coding for otoferlin, cause non-syndromic recessive ...
Muscular dystrophies (MDs) are a group of diseases that cause muscular and neurological disorders in human patients. They are associated with a multi-component complex called the Dystrophin Glycoprotein Complex (DGC). The ...
The ubiquitin proteasome pathway is one of the major protein degradation pathways in the cell. This pathway is essential for protein quality control and the regulation of the cell cycle. Proteins subjected to the ubiquitin ...