Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Advisor "Kühnel, Karin Dr."
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Structural, biochemical and computational studies on PROPPINs, proteins important in autophagy
(2015-12-16)PROPPINs (β-propellers that bind polyphosphoinositides) are conserved eukaryotic proteins that play an important role in autophagy. Yeast contains three PROPPINs: Atg18, Atg21 and Hsv2 (homologous with swollen vacuole ... -
Crystal Structure and Characterization of the SCOC Coiled Coil Domain
(2014-08-06)Autophagy is a conserved eukaryotic process for the degradation of cytosolic content. An expanding double layered membrane takes up part of the cytoplasm and matures to an autophagosomal vesicle. The autophagosome ... -
Insights into membrane binding of PROPPINs and Reconstitution of mammalian autophagic conjugation systems
(2013-06-24)Autophagy is a degradation pathway conserved in eukaryotes. Upon induction of autophagy a double layered membrane is formed de novo and engulfs the cytosolic content. After fusion of the membrane, an autophagosome vesicle ...