Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Advisor "Luther, Stefan Prof. Dr."
Now showing items 1-6 of 6
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Arrhythmia termination using Global Optogenetic Stimulation in ChR2 mice hearts
(2021-03-04)Cardiac arrhythmias represent a health threat worldwide that can end in sudden death. Treatments which include electrical shocks, anti-arrhythmic drugs and ablation show various disadvantages such as discomfort for the ... -
On Control of the Excitable Dynamics in the Heart
(2019-11-19)Ventricular fibrillation, a frequent cause of death, is a heart condition associated with complex patterns of electric activity on the heart surface. In spite of a century of research many aspects of how ventricular ... -
Influence of Heterogeneities on Waves of Excitation in the Heart
(2018-08-27)In this document the interplay of a single large heterogeneity in cardiac tissue and the excitation dynamics associated with ventricuar tachycardia is investigated. Methods from non-linear dynamics are used to investigate ... -
Intramural Visualization of Scroll Waves in the Heart
(2015-10-09)Despite extensive research, the fundamental biophysical mechanisms underlying severe heart rhythm disorders such as ventricular fibrillation remain poorly understood. Ventricular fibrillation is an acute and highly lethal ... -
NaV1.5 Modulation: From Ionic Channels to Cardiac Conduction and Substrate Heterogeneity
(2014-03-31)The work presented in this thesis is centered on characterizing macroscopic electrophysiological instabilities observed at the tissue level that emanate from perturbations affecting essentially the NaV1.5 channel in the ... -
Complex Structure and Dynamics of the Heart
(2013-10-02)Excitable media are a class of spatially extended biological and chemical systems, which display a characteristic type of pattern formation by supporting the propagation of nonlinear excitation waves. In the heart, plane ...