Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Advisor "Meinecke, Michael Prof. Dr."
Now showing items 1-7 of 7
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Molecular characterization of protein translocation pores
(2024-02-27)Within the intricate realm of intracellular protein transport, individual organelles are reliant upon precise and dedicated protein machineries, commonly referred to as translocon, to facilitate the translocation of proteins ... -
Molecular characterization of protein-dependent lipid transport during mitochondrial biogenesis
(2022-05-18)Mitochondria are comprised of two membranes, each with a unique lipid and protein composition, subdividing this organelle into the outer mitochondrial membrane (OMM), the intermembrane space (IMS), the inner mitochondrial ... -
Decoding and influencing mitochondrial inner membrane ultra-structure biogenesis
(2022-04-28)The Mitochondrion is a ubiquitous organelle known to be involved in a variety of vital cellular functions besides its central role in ATP synthesis such as, cellular metabolism, signalling and apoptosis. Dynamic in both ... -
Molecular investigation of mitochondrial inner membrane morphology
(2019-06-03)The mitochondrial inner membrane (MIM) is highly curved and displays a complex but extremely organised ultrastructure. It is subdivided into two morphologically, topologically, as well as functionally, distinct compartments. ... -
Molecular Details of Membrane Deformation by ENTH Domains
(2018-03-20)During clathrin mediated endocytosis (CME) cargo molecules are transported across the plasma membrane from the outer cell surface into the cytosol. In this process, the plasma membrane undergoes massive local remodeling ... -
Molecular Characterization of the Mitochondrial Presequence Translocase
(2018-01-31)In this thesis, multiple pore-lining amino acid residues of the mitochondrial presequence translocation channel Tim23 were identified as constituents of the channel’s cation filter by combining single channel electrophysiology ... -
Characterization of inner mitochondrial membrane architecture
(2016-08-26)The inner membrane of mitochondria is extensively folded and displays a complex architecture. Cristae junctions are highly curved tubular openings that separate the cristae membrane from the inner boundary membrane. They ...