Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Advisor "Rehfeldt, Florian Dr."
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Molecular DNA Sensors to Measure Distribution of Cytoskeletal Forces
(2020-08-24)Actin, a major cytoskeletal biopolymer in eukaryotic cells, is crosslinked into networks of filaments and bundles. These networks are largely responsible for the maintenance of cellular shape, rigidity, and mechanical ... -
Acto-myosin based mechano-sensitivity of cells - comparing human mesenchymal stem cells and differentiated cells
(2017-08-09)Within the last decades it was discovered that the cellular microenvironment plays an important role in cellular processes and cell fate can be directed by mechanical properties of the extracellular matrix (ECM), which can ... -
Structure and dynamics of stress fibers in adult stem cells
(2016-07-19)Since decades, the differentiation potential of adult human mesenchymal stem cells (hMSCs) is investigated. They feature the ability for differentiation into various cell types, like cartilage, fat, nerve, muscle and ... -
Mechanics of suspended cells probed by dual optical traps in a confocal microscope
(2015-12-02)Cells are sensitive to mechanical cues from their environment and at the same time generate and transmit forces to their surroundings. In this thesis, we quantitatively measured forces and elastic spring constants of ...