Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Advisor "Thumm, Michael Prof. Dr."
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Dissection of the molecular machinery of micro- and macronucleophagy
(2019-11-07)A highly conserved pathway required for cellular homeostasis, autophagy facilitates degradation and recycling of various cellular components. Involvement of autophagy in medical context has made associated research a highly ... -
Atg21 restricts Atg8 lipidation to a novel vacuole-phagophore contact site
(2019-07-01)Macroautophagy is a degradative membrane trafficking pathway that removes and recycles cellular components to maintain cellular homeostasis. Targets for degradation are a variety of cytosolic components including protein ... -
Atg26 is involved in selective autophagy of the major coat protein Gag of the S. cerevisiae virus L-A
(2016-01-22)Macroautophagy is a conserved catabolic pathway for the removal and recycling of cytosolic components, damaged or surplus organelles, protein aggregates or intracellular pathogens to maintain cellular homeostasis. It is ... -
Atg21 functions during autophagy as a scaffold for the E3 ubiquitin-‐like complex in Atg8 lipidation
(2015-01-23)Autophagy summarizes a family of intracellular lysosomal (vacuolar) degradative transport process. It is used for the removal and recycling of cytoplasm, protein aggregates and organelles to maintain cellular homeostasis. ... -
Identification of novel components involved in selective and unselective autophagic pathways
(2012-04-11)Autophagy is a ubiquitous protein degradation pathway in eukaryotic cells. As response upon nutrient starvation, cytosolic material and also whole organelles are engulfed by a double membrane-layered vesicle, the ...