Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Borchers, Annette Prof. Dr."
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PTK7 protein localization and stability is affected by canonical Wnt ligands
(2016-02-04)Wnt co-receptors have been shown to be endocytosed in response to Wnt proteins. However, the role of Wnt receptor internalization for Wnt signaling is a topic of ongoing research. Here we show that the Wnt co-receptor PTK7 ... -
Controlled levels of canonical Wnt signaling are required for neural crest migration
(2016-01-22)Canonical Wnt signaling has been shown to orchestrate the development of the neural crest (NC), a transient population of multipotent, migratory cells that generate a vast array of cell types. Canonical Wnt signaling is ... -
The transmembrane receptors Otk and Otk2 function redundantly in Drosophila Wnt signal transduction
(2013-06-11)Canonical and non-canonical Wnt signaling pathways have in common Frizzled (Fz) as the core Wnt receptor element. Recent findings implicate that not only the choice of Wnt ligands, but also the presence of additional ...