Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Boretius, Susann Prof. Dr."
Now showing items 1-12 of 12
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Development of Methods for Cardiac Tissue Characterization Using Magnetic Resonance Imaging in Animal Models
(2024-09-26)Cardiovascular diseases (CVDs) are the primary cause of death and disability globally. The progression of CVDs is often associated with functional and structural alterations, including reduced myocardial contractility, ... -
Behavioral analyses in translational neuropsychiatric research
(2024-07-05)Cognitive impairment frequently co-occurs in a variety of neuropsychological disorders, making it an increasing burden to the affected individuals, their relatives, and society in general. Diagnostic procedures usually ... -
Structural and functional connectivity in patients with major depressive disorder undergoing accelerated intermittent theta burst stimulation
(2024-06-05)Major depressive disorder (MDD) is one of the most prevalent mental health conditions, primarily characterized by depressed mood and loss of interest or pleasure. Cognitive impairments, including psychomotor agitation ... -
Multi-nuclear magnetic resonance imaging and spectroscopy of lithium in the brain
(2024-02-23)Equipped with only three protons, lithium stands as one of the most unexpected drug discoveries in history. Despite its initial FDA approval in 1970, lithium's precise mechanism for regulating mood remains largely elusive. ... -
Influence of Interictal Epileptiform Activity on Language Networks in Children with Rolandic Epilepsy or Dyslexia
(2024-01-05)Self-limited Epilepsy with Centrotemporal Spikes (SeLECTS) is the most common genetic epilepsy in children. It is characterized by seizures remission in puberty and highly frequent interictal epileptiform discharges (IEDs) ... -
Neurovascular coupling in a central nervous system white matter tract
(2022-08-08)Neurovascular coupling is the process by which blood vessels dilate upon increased neuronal activity. It has been extensively studied in the murine grey matter and there are several models explaining possible molecular ... -
White matter integrity of the frontal brain and its relevance for catatonia and executive function
(2021-11-22)Catatonia is a CNS derived psychomotor syndrome comprising disturbed volition and aberrant motor and behavioral features. Targeted and effective treatment today is scarce and further impeded by its heterogeneous clinical ... -
Environmental and genetic correlates of neuropsychiatric diseases and the role of erythropoietin/hypoxia in the brain as potential treatment targets
(2021-06-15)Neuropsychiatric disorders are relatively frequent and present a considerable burden to affected individuals and society. Disease etiology is often complex and patients exhibit large heterogeneity regarding disease causing ... -
Constitutive Modeling for Tissue Engineered Heart Repair
(2020-10-27)Computer-aided therapy design is an intricate endeavor intertwining all scales from molecules to cells and tissues to organs. Changing one such component in a living system can have far-reaching effects, diffcult to ... -
Modulation of neuronal excitability in the cognitive control network by electrical stimulation
(2020-05-19)The cognitive control network is key to thriving in a complex and ever-changing world. By electrically stimulating two hubs of this network, their causal involvement in the cognitive control network was shown. The stimulation ... -
Erythropoietin as a driver of neurodifferentiation, neuroplasticity and cognition – A continuum view of the neuronal lineage
(2019-12-05)Erythropoietin (EPO), named after its role in hematopoiesis, has been best studied in the hematopoietic system. Studies emphasizing the expression of EPO in the central nervous system have sparked an interest in its role ... -
Investigation of myelin maintenance and turnover by inducible MBP knock-out in adult mice
(2019-11-11)The turnover and maintenance of myelin in the adult CNS Myelin is a multilayered membrane structure generated by oligodendrocytes in the CNS that insulates and supports axons. While most of the oligodendrocyte population ...