Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Bucher, Gregor Prof. Dr."
Now showing items 1-14 of 14
-
Conservation and divergence of the retinal homeobox genetic neural lineage between Drosophila melanogaster and Tribolium castaneum
(2024-06-25)Brains are the central organ integrating sensory information and orchestrating behaviour. Their function and development are of great scientific interest, but their enormous complexity makes them difficult to study. The ... -
Identification of a novel subnetwork involved in eye size variation between Drosophila melanogaster and D. mauritiana
(2022-04-07)The Mendelian genetics concept relies on simple genotype-phenotype relationships with few genes having major effects on the phenotype. However, many traits evolve by a combination of variation in many genomic loci with ... -
Evaluation of genetic engineering and genome editing tools to develop multifactorial reproductive sterility or killing sperm systems for the improvement of the Sterile Insect Technique
(2020-11-20)Insects fulfill fundamental roles for the preservation of ecosystems such as pollination, but also represent key agricultural pests and human disease vectors accounting for immense economic losses and approximately one ... -
Molecular Mechanisms of Germ Plasm Anchoring in the Early Zebrafish Embryo
(2020-08-14)Zebrafish germline is specified early during embryogenesis by inherited maternal RNAs and proteins called germ plasm. Only those cells containing germ plasm will become part of the germline, whereas other cells will ... -
The Evolutionary Establishment of Apomixis in Hybrids of the Ranunculus auricomus Complex: Developmental and Cytogenetic Studies
(2020-06-16)In plant evolution, polyploidization and hybridization are important forces that both effectively contribute to developmental alterations. Asexual seed formation, known as apomixis, is mainly found in polyploid and/ or ... -
Role of mechanosensitive ion channels in coordinated epithelial cell dynamics in Drosophila
(2019-11-20)Epithelial cells are able to sense and mechanically respond to the forces and movements generated and transmitted through their neighbors. These forces are multicellular at the tissue level, and are transmitted via multimeric ... -
Evolution of central complex development: Cellular and genetic mechanisms
(2019-11-11)Brains are conserved between insect species, as they consist of a set of anatomically similar areas, or neuropils. Simultaneously, these neuropils differ in size, shape, position and developmental timing between insect ... -
The nuclear envelope proteins Kugelkern and Narf and their putative role in aging
(2018-10-26)Lamins are type V intermediate filaments and represent the major constituent of the nuclear lamina. Mutations in the laminA/C gene as well as in other nuclear envelope associated proteins lead to a series of human genetic ... -
Developmental Studies on Eye Types and Pedipalps in Parasteatoda tepidariorum
(2017-12-21)Arthropods are by far the most species rich phylum in the animal kingdom and their evolutionary success is at least in part rooted in their diverse morphology. Despite these morphological differences, arthropods share a ... -
Epigenetic regulation of osteoblast differentiation
(2017-06-07)Proper temporal epigenetic regulation of gene expression is essential for cell fate determination and tissue development. However, epigenetic mechanisms involved in control of bone-specific transcriptional programs remain ... -
Morphogenesis and Genetic Regulation of the Insect Head
(2016-09-30)Natural selection and the struggle for ecological niches were the driving force for the origin of a tremendous number of animal groups with different body shapes. The segmental organization of insects enhanced their ... -
Functional analysis of Prdm14 during Xenopus embryogenesis
(2016-06-23)Prdm14 is a member of the conserved family of Prdm proteins, which are emerging as crucial regulators of multiple early developmental processes and diseases. Members of the Prdm family are characterized by the presence ... -
Probing roles of TRPML in Drosophila hearing
(2016-01-15)Several transient receptor potential (TRP) channels have been implicated in Drosophila hearing, including the TRPN channel NOMPC, the TRPVs Nan and Iav, and the TRPA members Pyx and Pain. Here I report that fly hearing ... -
Regulation of H2B Monoubiquitination Pathway in Breast cancer
(2015-01-23)H2B monoubiquitination (H2Bub1) regulation via CDK9-WAC-RNF20/40 axis has been well illustrated. It is interesting to determine the upstream regulators which dictate the process of monoubiquitination of H2B. On further ...