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Now showing items 1-6 of 6

    • Characterization of RNA-modifying enzymes and their roles in diseases 

      Warda, Ahmed (2017-11-29)
      More than 150 types of chemical modifications have been identified in cellular RNAs (collectively called ‘’the epitranscriptome’’), and such modifications have emerged as important regulators of gene expression. Despite ...
    • Development of new methods in fluorescence microscopy 

      Lin, Chao-Chen (2015-12-02)
      In recent years, advancements in single-molecule imaging techniques have enabled scientists to study in great detail the cells and relevant physiological processes, including neurons and the communication between them. ...
    • Interactions and functions of RNA-binding proteins 

      Kretschmer, Jens (2018-04-13)
      Alongside several well-known modifications in DNA and proteins, more than 100 different types of chemical modification are also found in cellular RNAs. RNA modifications can influence the secondary structure and interactions ...
    • Paramagnetic tools for the structural analysis of high molecular weight proteins 

      Camacho Zarco, Aldo Roman (2015-12-10)
         Paramagnetic effects provide important structural and dynamic information of biomolecules. However, the attachment of lanthanides through small chelating organic molecules to proteins (the most common way to obtain ...
    • Structural investigation of functional nucleic acids 

      Mieczkowski, Mateusz (2021-06-30)
      DNA enzymes, also known as deoxyribozymes, are synthetic single-stranded DNA molecules able to catalyze chemical reactions. There are two main reasons for studying deoxyribozymes: their practical value in various applications, ...
    • Structure-function analysis of human nucleotide excision DNA repair 

      Kokic, Goran (2021-04-09)
      An average human cell accumulates tens of thousands of DNA lesions per day. Therefore, DNA repair pathways are set up to continuously proofread the DNA and correct DNA lesions, thus ensuring accurate expression and ...