Dokumente GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften nach Gutachter "Hülsmann, Swen Prof. Dr."
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Metabolism of oligodendrocytes and its involvement in axo‐glia interaction
(2019-03-12)In white matter, axonal energy homeostasis critically depends on glial support. Failure in glial-mediated delivery of metabolic substrates into the axonal compartment results in axonal energy deficit and may anticipate ... -
The role of oligodendrocytes in higher-order circuit functions
(2018-11-12)The historical conception of glial cells as the ‘glue’ that holds the brain together has dramatically changed in the last years. The glia plays an active role in several mechanisms related to information processing in the ... -
Untangling neuronal diversity: a quantitative electrophysiological and morphological characterization of VIP expressing interneurons
(2017-03-21)VIP expressing interneurons are an essential component of cortical circuitry. This distinct subgroup of inhibitory interneurons was always described as the most heterogeneous subgroup of inhibitory interneurons. However, ... -
Functional connectivity of layer II/III and V GABAergic Martinotti cells in the primary somatosensory (barrel) cortex of mice
(2016-02-16)Although they represent only a small portion of cortical neurons, inhibitory interneurons take a major role in controlling the activity of cortical excitatory cells and, hence, cortical processing. The interaction of ... -
GABA and glycine co-transmission in the developing mouse respiratory network
(2014-11-18)Inhibitory neurons in the pre-Bötzinger complex - a kernel for respiratory rhythm generation, are involved in the respiratory rhythm modulation. The co-transmission of GABA and glycine has been reported in different brain ... -
Identifying Target Genes related to Respiratory Network Dysfunction in a Mouse Model for the Rett Syndrome
(2013-02-05)Rett Syndrome is a severe neurological disorder caused by mutations in the X chromosome-linked MECP2 gene, which encodes the transcription factor methyl CpG binding protein 2 (MeCP2). Symptoms become obvious during early ... -
Astroglial glutamate transporters are essential for maintenance of respiratory activity in the rhythmic slice preparation
(2012-01-25)Astrocytes are the major type of glial cells in the brain and were already described in the 19th century by Rudolf Virchow. The physiological investigation of astrocytes has long been hampered by difficulties to identify ...