Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Halyna, Shcherbata Dr."
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Acetyltransferase TIP60/KAT5 regulates the Drosophila Circadian Clock
(2016-10-14)Endogenous clocks control behavioral and physiological processes in a rhythmic fashion exhibiting periodicity of ~24 h. Drosophila exhibits a robust rhythm in activity/rest patterns which is controlled by circadian pacemaker ... -
A regulatory network of Mdm2 and members of the Polycomb Group (PcG) family
(2016-01-22)The E3 ubiquitin ligase MDM2 is the most well-known physiological antagonist of the tumor suppressor P53. P53 induces cell cycle arrest or apoptosis in the case of DNA damage, whereas MDM2 targets it for proteasomal ... -
Role of BRD4 and histone acetylation in estrogen receptor-positive breast cancers
(2015-09-10)The estrogen receptor-α (ERα) acts as a nuclear transcription factor to promote estrogen-induced transcription and plays a central role in the progression of ER-positive tumors. ERα binds to the consensus DNA elements ... -
Role of cellular dynamics, adhesion and polarity in the context of primordial germ cell migration in Xenopus laevis embryos
(2014-02-11)Directional cell migration is an intensively studied process relevant for both normal development of an organism as well as for a number of pathological conditions such as chronic inflammation and cancer. Primordial germ ...