Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Lange, Adam Dr."
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NMR Spectroscopy of the Tau-Microtubule Interaction
(2015-12-10)Tau is an intrinsically disordered, microtubule associated protein and is responsible for the promotion of microtubule (MT) formation and stabilization. The human Tau protein has six different isoforms, which are expressed ... -
13C sparse labeling for solid-state NMR investigations of biomolecular systems
(2014-12-16)This thesis refers to 13C sparsely labeled strategies, including protein structure characterization on two different biomolecular systems, to obtain structural information via 13C-13C and 13C-15N correlations by solid-state ... -
Structural insights into Arginine-Serine rich proteins and N-H spin-spin coupling constants
(2013-11-27)This thesis is constituted of two parts. In the first part of this thesis, I studied the structural phenomena of SR protein phosphorylation. The serine/arginine-rich (SR) protein family plays multiple functions in the whole ... -
Molecular Mechanisms of Tau Protein Aggregation Inhibition
(2013-11-11)Of all neurodegenerative diseases, Alzheimer´s Disease is the most widespread dementia syndrome, exhibiting progressive memory loss and intellectual abilities. One of the pathological hallmarks of this disease is associated ...