Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Luther, Stefan Prof. Dr."
Now showing items 1-8 of 8
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Intercellular Coordination in Epithelial Morphogenesis
(2022-07-26)During the development of an embryo, tissue rearrangements are driven by the precisely coordinated activity of thousands of cells. How this high degree of organization is achieved and regulated is one of the most important ... -
Arrhythmia termination using Global Optogenetic Stimulation in ChR2 mice hearts
(2021-03-04)Cardiac arrhythmias represent a health threat worldwide that can end in sudden death. Treatments which include electrical shocks, anti-arrhythmic drugs and ablation show various disadvantages such as discomfort for the ... -
Higher-Dimensional Extensions of Nonlinear Inverse Reconstruction for Magnetic Resonance Imaging
(2020-02-05)Even though magnetic resonance imaging (MRI) has become progressively faster in recent years, acquisition speed is still a problem in current clinical settings. Physiological constraints such as gradient-induced peripheral ... -
On Control of the Excitable Dynamics in the Heart
(2019-11-19)Ventricular fibrillation, a frequent cause of death, is a heart condition associated with complex patterns of electric activity on the heart surface. In spite of a century of research many aspects of how ventricular ... -
Influence of Heterogeneities on Waves of Excitation in the Heart
(2018-08-27)In this document the interplay of a single large heterogeneity in cardiac tissue and the excitation dynamics associated with ventricuar tachycardia is investigated. Methods from non-linear dynamics are used to investigate ... -
Intramural Visualization of Scroll Waves in the Heart
(2015-10-09)Despite extensive research, the fundamental biophysical mechanisms underlying severe heart rhythm disorders such as ventricular fibrillation remain poorly understood. Ventricular fibrillation is an acute and highly lethal ... -
NaV1.5 Modulation: From Ionic Channels to Cardiac Conduction and Substrate Heterogeneity
(2014-03-31)The work presented in this thesis is centered on characterizing macroscopic electrophysiological instabilities observed at the tissue level that emanate from perturbations affecting essentially the NaV1.5 channel in the ... -
Complex Structure and Dynamics of the Heart
(2013-10-02)Excitable media are a class of spatially extended biological and chemical systems, which display a characteristic type of pattern formation by supporting the propagation of nonlinear excitation waves. In the heart, plane ...