Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Söding, Johannes Dr."
Now showing items 1-6 of 6
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Dynamics and regulation of the mitochondrial translation machinery
(2024-11-15)Throughout this project, we have successfully established and implemented a ribosome profiling protocol tailored for examination of translating mitochondrial ribosomes, thereby affording a deeper understanding of mitochondrial ... -
Dynamics and Machine Learning Inference using Memory in Stochastic Biochemical Reaction Networks
(2024-06-24)In this thesis we study the dynamics of non-equilibrium stochastic chemical reaction networks with a special focus on biochemical networks. In the regime of large intrinsic noise where the numbers of participating molecules ... -
Molecular Dynamics Studies of Permeation and Gating Mechanisms in Potassium Channels
(2023-04-19)Potassium (K+) channels contribute to diverse physiological activities, representing an indispensable part of living organisms. A thorough understanding of different aspects of permeation mechanisms and gating in K+ channels ... -
From annotation to bacterial data models
(2022-06-24)Science and technological advancements walk side-by-side and with the recent emergence of novel high throughput techniques, the necessity to have specialized data structures to host and represent the complex and high variety ... -
Statistical methods for biological sequence analysis for DNA binding motifs and protein contacts
(2021-09-21)Over the last decades a revolution in novel measurement techniques has permeated the biological sciences filling the databases with unprecedented amounts of data ranging from genomics, transcriptomics, proteomics and ... -
Quantitative Modeling of RNA-Protein Interactions
(2021-05-07)RNA-binding proteins (RBPs) impact every aspect of RNA metabolism including RNA transcription, maturation, export, localization, translation, and stability. Specific RNA-protein interactions therefore play a central role ...