Dokumente GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften nach Gutachter "Schmitt, Hans Dieter Dr."

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    • Mechanisms of synaptic plasticity mediated by Clathrin Adaptor-protein complexes 1 and 2 in mice 

      Mishra, Ratnakar (2019-06-13)
      Clathrin adaptor protein complexes 1 and 2 (AP1 and AP2) have essential functions in synaptic vesicle (SV) recycling. In all cell types and tissues, AP1 mediates TGN/endosome protein sorting via clathrin-coated-vesicles ...

    • The role of mammalian TRC40 in membrane-protein targeting and chaperoning 

      Coy Vergara, Francisco Javier (2019-05-24)
      Tail-anchored (TA) proteins are distinguished from other membrane proteins due to their particular topology. The best-characterized pathway for the targeting of TA-proteins is the GET pathway in yeast or the TRC pathway ...

    • Role of WRB protein in cardiac function 

      Rivera Monroy, Jhon Erick (2017-08-24)
      The mammalian TRC40 system is a conserved pathway responsible for the post-translational targeting of tail-anchored proteins, which are characterized by a single transmembrane domain at the C-terminus and an N-terminus ...

    • Characterization of the Dynein-Dynactin Interaction 

      Findeisen, Peggy (2015-02-13)
      In eukaryotic cells many biological processes like cell division, the distribution of vesicles and organelles require the dynamic rearrangement of molecules and cellular components. These rearrangements are controlled by ...