Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Schuh, Reinhard Prof. Dr."
Now showing items 1-10 of 10
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Role of mechanosensitive ion channels in coordinated epithelial cell dynamics in Drosophila
(2019-11-20)Epithelial cells are able to sense and mechanically respond to the forces and movements generated and transmitted through their neighbors. These forces are multicellular at the tissue level, and are transmitted via multimeric ... -
Cellular stress induces RIS dependent sleep and ALA dependent sedation via EGF receptor signaling in Caenorhabditis elegans
(2019-07-15)Why do we sleep? This question is still unsolved, although sleep is such a fundamental behavioral state in all organism with a nervous system. Several physiological mechanisms, like memory consolidation, metabolic waste ... -
The nuclear envelope proteins Kugelkern and Narf and their putative role in aging
(2018-10-26)Lamins are type V intermediate filaments and represent the major constituent of the nuclear lamina. Mutations in the laminA/C gene as well as in other nuclear envelope associated proteins lead to a series of human genetic ... -
Head versus tail: germ cell-less initiates axis formation via homeobrain and zen1 in a beetle
(2018-08-27)The iBeetle screen project: Christiane Nüsslein-Volhard and Eric Wieschaus performed the first saturated forward genetic screen using random mutagenesis to identify genes important for embryonic development in Drosophila ... -
Role of the nuclear lamina for stem cell mediated homeostasis
(2016-11-22)The nuclear lamina is a protein meshwork at the inner side of the inner nuclear membrane and connects to essential cellular structures like chromatin, the nuclear pore complex and the cytoskeleton. The nuclear lamina is ... -
Spatio-temporal Approach to Transport Dynamics in the Mammalian Ventricular System
(2015-02-19)This thesis addresses circadian regulation of solute transport systems in the brain ventricular system. It was found that transport of solutes between blood and the ventricular lumen are subjected to circadian regulation ... -
Localisation and function of Slam in the early Drosophila embryo
(2014-11-06)Embryogenesis of many insects starts with a syncytial stage characterised by 13 rapid nuclear divisions. During the following interphase, the plasma membrane of the embryo invaginates between each nucleus to give rise to ... -
Pancreatic β-Cell Regeneration in TIF-IA Knockout Mice
(2014-09-30)As the sole source of insulin production in body, pancreatic β-cells play an essential role in glucose homeostasis. Diabetes mellitus is a chronic disease characterized by loss, reduction, and/or malfunction of β-cell mass. ... -
Identification and functional characterization of PTK7 ligands in Xenopus laevis
(2011-10-26)Wnt signaling pathways are evolutionary conserved and regulate numerous processes in both developing and adult organisms. The canonical Wnt signaling pathway regulates cell proliferation ... -
The role of the novel endosomal protein Rush hour (CG14782) in endosomal trafficking in Drosophila melanogaster
(2011-03-29)Endocytosis regulates multiple cellular processes, including the protein composition of the plasma membrane, intercellular signaling and cell polarity. Cell polarity is defined by asymmetric ...