Dokumente GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften nach Gutachter "Soeding, Johannes Dr."
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The role of proteasome generated spliced peptides in the adaptive immune response
(2022-05-20)CD8+ T-cells are the crucial component of the adaptive immune system as they survey the cells of the body for the signs of pathogens or tumours and eliminate them when necessary. To do this, T-cells recognise short antigenic ... -
Chromatin reorganization, signaling responses and non-coding RNA regulators in homeostasis and senescence
(2022-04-21)In mammalian cells, a relatively limited fraction of genetic information is utilized in a variety of ways to give rise to distinct cellular phenotypes. Thus, the genotype essentially acts as input for multilayered regulatory ... -
Discovery and prediction of protein binding sites in DNA and RNA sequences using Bayesian Markov models
(2021-04-23)Transcription factors control the essential step of gene expression via recognizing the over- represented binding sites (or motifs) on the genome. One crucial task is to accurately predict these binding sites on the ...