Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Stadelmann-Nessler, Christine Prof. Dr."
Now showing items 1-8 of 8
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The role of RNA in synaptic physiology and neurodegeneration in synucleinopathies
(2025-01-23)Synucleinopathies are neurodegenerative disorders characterised by the pathological accumulation and aggregation of the protein alpha-synuclein (aSyn). Parkinson’s disease (PD), Dementia with Lewy bodies (DLB), multiple ... -
Pairing transcranial direct current stimulation and mindfulness meditation in the treatment of fibromyalgia
(2024-08-22)The lack of effective treatments for managing pain and associated symptoms in fibromyalgia (FM) poses both a clinical challenge and an economic burden on the health sector. Typical FM therapies include an array of ... -
Investigations of Synaptic Alterations in Models of Parkinson’s Disease
(2024-07-02)Alpha-synuclein (aSyn) is a presynaptic protein implicated in physiological synaptic roles, though its precise function is largely unknown. In Parkinson's disease (PD), the initial pathological events often involve synaptic ... -
A Multidisciplinary Approach to Neuropathic Pain: Assessing Tactile Sensation and Neuroma Pain Factors
(2023-07-18)Neuropathic pain is a complex and often debilitating condition. Distally from the injury site, missing input contributes to deafferentation pain, while proximally, neuroma formation leads to peripheral and central ... -
Ultrastructural study of synaptic vesicle dynamics in murine inner hair cell ribbon synapses under sustained stimulation
(2023-07-11)Transmission of auditory information relies in the correct functioning of inner hair cell (IHC) rib-bon synapses, which mediate synaptic vesicle release in an indefatigable manner. The name-giving synaptic ribbon and the ... -
Crosstalk between the lung microenvironment and CNS autoimmunity
(2023-05-08)The contribution of the lung in shaping CNS autoimmunity is gaining relevance in the last years. Central nervous system (CNS) reactive T cells can acquire in the lung the potential to invade the CNS in experimental ... -
The role of astrocytes for oligodendrocyte death and remyelination
(2013-01-30)Astrocytes are the most abundant cells in the central nervous system (CNS) with wide-ranging functions. The first part of my thesis deals with Neuromyelitis optica (NMO), an inflammatory demyelinating disease of the CNS. ... -
Damage and Repair in Experimental Cortical Demyelination
(2010-11-04)Remyelination represents an important self repair mechanism in demyelinating diseases such as multiple sclerosis (MS). The intrinsic regenerative potential of the cerebral cortex is ...