Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Zimmermann, Wolfram-Hubertus Prof. Dr."
Now showing items 1-6 of 6
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Development of Methods for Cardiac Tissue Characterization Using Magnetic Resonance Imaging in Animal Models
(2024-09-26)Cardiovascular diseases (CVDs) are the primary cause of death and disability globally. The progression of CVDs is often associated with functional and structural alterations, including reduced myocardial contractility, ... -
Phenotypic and Functional Characterization of Natural Killer Cell Receptors in Human and Rhesus macaque
(2024-02-05)Activating killer immunoglobulin-like receptors (KIRs) cannot transmit signals directly but through signaling motifs. Since human activating KIRs lack signaling molecules, their transmembrane lysine residue pairs with ... -
Cystic Fibrosis as a model use case for implementing cell based disease models in systems medicine
(2022-11-22)In the last two decades, tremendous progress has been made in producing large amounts of biological and biomedical data in a time- and cost-effective manner. Along with the increasing amount of data has come the requirement ... -
Constitutive Modeling for Tissue Engineered Heart Repair
(2020-10-27)Computer-aided therapy design is an intricate endeavor intertwining all scales from molecules to cells and tissues to organs. Changing one such component in a living system can have far-reaching effects, diffcult to ... -
Erythropoietin as a driver of neurodifferentiation, neuroplasticity and cognition – A continuum view of the neuronal lineage
(2019-12-05)Erythropoietin (EPO), named after its role in hematopoiesis, has been best studied in the hematopoietic system. Studies emphasizing the expression of EPO in the central nervous system have sparked an interest in its role ... -
Genetic and autoimmune modulators of brain function in neuropsychiatric illness and health
(2018-06-15)In the present thesis, the synergetic interaction between the nervous and immune systems and the potential pathological outcomes mediated by autoimmune processes targeting the brain was addressed, with a particular focus ...