Browsing Human- und Zahnmedizin by Advisor "Binder, Claudia Prof. Dr."
Now showing items 1-8 of 8
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Einfluss der sauren und der neutralen Sphingomyelinasen auf Produktion und Zusammensetzung extrazellulärer Vesikel von Mamma-Karzinom-Zelllinien
(2021-07-06)Extracellular vesicles, including microvesicles and exosomes, are important mediators in cell-cell-communication, both in physiological and pathological processes. Due to their diagnostic and therapeutic potential they ... -
Expression von Genen des WNT-Signalwegs in humanen Makrophagen nach MCF-7 Ko-Kultivierung und in murinen Makrophagen nach Mikrovesikel-Stimulation
(2019-09-19)The interaction between malignant cells and stroma cells contributes in a crucial way to their biological activity. In breast cancer there is an association between activation of the canonical WNT-Pathway and aggressive ... -
Etablierung der Organotypischen Hirnschnitt-Kokultur als Tumor-Invasionsmodell
(2013-02-12)The aim of this study is to contribute significantly to our understanding of cerebral metastasis formation. The process of the metastatic site has barely been investigated yet, in particular the role of resident cells. It ... -
Wnt-Signale in der Invasivität von Hodgkin-Lymphomen
(2012-07-04)For the diffusion of lymphoma cells, migration and invasion are an important prognostic factor. Following the function of their benign progenitor cells, the lymphoma cells are disseminated already in early stages of ... -
Die Bedeutung von Dishevelled in der Wnt-5a-induzierten Signaltransduktion.
(2011-11-02)Wnt proteins are secreted glycoproteins regulating biological processes in cell migration and tissue patterning during embryogenesis via highly conserved signaling pathways and are often ... -
Veränderungen der Morphologie und des Migrationsverhaltens unter dem Einfluss von Wnt5a und DKK-1 bei Brustkrebszellen
(2010-10-20)Focussing on interactions between tumor cells and surrounding stromal cells in tumor progression it has recently been shown that Wnt5a enhances invasiveness of low invasive MCF-7 breast ... -
Der Wnt-Signalweg in der Makrophagen-induzierten Invasion von Brustkrebszellen
(2010-10-07)The interactions between malignant tumor cells and the surrounding benign stromal cells are an important factor in tumor biology. Wnt proteins are potential candidates to mediate this ... -
Mikroglia fördert die Invasivität von Karzinomzellen
(2009-12-15)Brain metastases are the most prevalent tumors of the CNS and predominantly deriving from lung and breast cancer. CNS metastasis is increasing due to impaired primary therapy, however, ...