Browsing Human- und Zahnmedizin by Advisor "Ellenrieder, Volker Prof. Dr."
Now showing items 1-4 of 4
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Mechanismen der Tumorsuppression und Resistenzüberwindung einer therapeutischen GSK-3β- Inhibition im Pankreaskarzinom
(2025-02-17)Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive types of human cancer with a five-year survival of only 11%. Recent studies have shown that PDAC results from a successive accumulation of different ... -
Die Rolle der Glykogen Synthase Kinase 3β in der Regulation von DNS-Schäden und Chemotherapieresistenz im Pankreaskarzinom
(2024-09-24)Pancreatic carcinoma is one of the most aggressive solid tumour types and is characterized by pronounced molecular heterogeneity. Research is continuing into molecularly definable subgroups that are suitable for targeted, ... -
The role of the ROBO 3 signaling pathway in pancreatic cancer plasticity
(2022-09-06)Pancreatic ductal adenocarcinoma remains one of the most aggressive cancers with a 5-year survival rate below 10 %. Particularly, the clinical outcome of metastatic pancreatic cancer is extremely poor with a dismal 5-year ... -
Urokinase-type plasminogen activator receptor contributes to chemosensitivity and epithelial-to-mesenchymal transition in PDAC
(2020-10-26)Purpose: Pancreatic ductal adenocarcinoma (PDAC) is the most frequent maliganancy of the pancreas and the fourth most lethal cancer with a 5-year overall survival rate of < 5 %. Patients with a gene amplification in the ...