Blättern Human- und Zahnmedizin nach "Grade, Marian Dr." Betreuer
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Applikation der Comparativen Genomischen Hybridisierung (CGH) zur Vorhersage des Ansprechens von Rektumkarzinomen auf neoadjuvante Radiochemotherapie
(2011-10-12)Introduction - Standard treatment of rectal cancer patients in UICC stages II and III comprises preoperative chemoradiotherapy followed by radical surgery. But there is a wide spectrum of ... -
Der Einfluss von NR3C1 und PDK4 auf das Wachstum kolorektaler Tumorzellen
(2012-09-12)Colorectal cancer originates from normal mucosa cells as a result of genetic alterations that cause changes in their differentiation status and in the control of cell growth. Understanding the molecular mechanisms of ... -
Relevanz des Wnt/β-Catenin-Signalwegs für die Radiotherapieresistenz des kolorektalen Karzinoms
(2016-07-11)The clinical response of rectal carcinomas to preoperative radiotherapy is highly heterogeneous, ranging from complete remission to total resistance. Unfortunately, patients with a resistant tumour are challenged with a ... -
Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy
(2014-09-25)A considerable percentage of rectal cancers are resistant to standard preoperative chemoradiotherapy. Because patients with a priori-resistant tumors do not benefit from multimodal treatment, understanding and overcoming ...