Blättern Human- und Zahnmedizin nach "Strutz, Frank Prof. Dr." Betreuer
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Die Rolle von Bone Morphogenetic Protein 4 und 7 bei der hypertensiven Nephrosklerose
(2012-11-07)Bone Morphogenetic Proteins (BMP) are members of the transforming growth factor (TGF-β) superfamily. In several animal experiments BMP-7 has shown beneficial effects in protecting kidney function in chronic kidney disease. ... -
Bedeutung der Blockade des lokalen Angiotensinsystems für die chronisch progrediente Niereninsuffizienz im Rahmen der Alport-Nephritis
(2012-08-30)The alport syndrome is the second most common hereditary renal disease, that is characterized by chronic and progressive renal failure. The main therapeutic focus at present is to delay the progression of the disease, since ... -
Effekte von Calcitriol auf die renale Fibrogenese
(2012-05-11)Calcitriol may decrease extracellular matrix accumulation in animal models of progressive kidney disease. The mechanisms are only partially understood. In order to understand the antifibrotic effects of calcitriol, we ... -
Regulation der Nestinexpression bei der epithelial-mesenchymalen Transition
(2012-01-25)The process of epithelial-mesenchymal transition (EMT) has long been known as one of the potential main factors in the formation of fibrous tissue. This investigation analyzed the relationship ... -
Der Einfluss von Interleukin-1 und des Interleukin-1-Rezeptorantagonisten (Anakinra) auf die epithelial-mesenchymale Transition von Tubulusepithelzellen in vitro
(2011-09-28)The end stage renal disease is one of the central problems in nephrology. The worldwide prevalence of chronic kidney disease is rising annually. The process of renal fibrogenesis is thereby ... -
HGF als anti-fibrotisches Agens: Effekte der Überexpression in renalen Fibroblasten und Tubulusepithelzellen
(2010-11-03)Chronic renal disease is affected by tubular interstitial fibrosis and lead to end stage renal failure. Mediated by chemokines inflammatory cells are recruited, proinflammatory mediators ... -
Die Bedeutung von Risikofaktoren für das Auftreten von Komplikationen nach Nierenbiopsie
(2009-12-09)Bleeding complications are the main problem of percutaneous renal biopsy. The risk of postbiopsy bleeding is still difficult to predict. Many parameters have therefore been tested in ...