Dokumente Human- und Zahnmedizin nach Gutachter "Bleckmann, Annalen Prof. Dr."
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MET-Alterationen als therapeutisches Target bei metastasierten kolorektalen Karzinomen
(2024-02-09)Introduction: An enhanced understanding of the molecular pathways driving oncogenesis has yielded an increasing number of potential therapeutic targets. MET amplification has been shown to be involved in angiogenesis, ... -
Analyse von Markerproteinen für Plasmamembran-abgeleitete Mikrovesikel
(2023-07-05)Cells are known to secrete extracellular vesicles (EVs) into their microenvironment. EVs act as mediators of intercellular communication, can travel long distances, and are involved in various ways in the progression and ... -
Wirbelsäulenmetastasen – Studie zur Inzidenz neurologischer Defizite mit und ohne vorbekannten Primärtumor
(2023-05-31)Spinal metastases are present in up to 10% of patients with malignancies. In patients who present with metastases in the spine, about one fifth have not previously had a known primary tumour. We took these two elements as ... -
Klinische Charakteristika, laborchemische Parameter und deren prognostische Bedeutung für Therapieansprechen und Überleben bei Patienten mit thrombotischen Mikroangiopathien
(2023-01-27)This dissertation deals with the clinical picture of TMA (TTP, STEC-HUS, aHUS and secondary TMA). The first question of the thesis deals with laboratory chemical parameters. This dissertation uncovers some aspects of TMA ... -
FGFR-Alterationen in primären und oligometastasierten kolorektalen Karzinomen
(2020-11-03)The outcome of metastatic colorectal cancer patients is up to now unsatisfactory and there is a need for effective therapeutic options. Fibroblast growth factor receptor (FGFR) and FGF ligand alterations have been investigated ...