Dokumente Human- und Zahnmedizin nach Gutachter "Döppner, Thorsten Roland Prof. Dr."
Anzeige 1-9 von 9
-
Automatisierte Thrombuserkennung anhand dünnschichtig rekonstruierter CCT-Schnittbilder
(2023-06-26)In Germany, around 250,000 people suffer a stroke every year. Depending on its severity and extent, a stroke leads to tissue damage and neurological deficits. To evaluate a therapeutic option in the form of intravascular ... -
Diagnostischer und prognostischer Stellenwert des Biomarkers Galectin-3 bei diastolischer Dysfunktion und Herzinsuffizienz mit erhaltener LV-Funktion –Ergebnisse der DIAST-CHF-Studie
(2020-10-28)Background: Diagnosis of heart failure with preserved ejection fraction (HFpEF) is challenging and extensive. However, it is relevant due to high prevalence. Currently, there is no therapy. The biomarker Galectin-3 is part ... -
Der Einfluss von Lithium auf die Bluthirnschrankenintegrität nach zerebraler Ischämie der Maus
(2022-04-08)Lithium wird seit Jahrzehnten bei der Behandlung von bipolaren Affektstörungen, Manie, Depression und Cluster-Kopfschmerz verwendet. Zusätzlich zeigte die Gabe von Lithium auch in einer Vielzahl präklinischer Tierexperimente ... -
Extracellular vesicles derived from adipose mesenchymal stem cells (AMSCs) reduce autophagic flux via microRNA-25-3p transfer after ischemic stroke
(2022-03-03)Causal therapy of ischemic stroke remains available to only a minority of patients despite the success of systemic thrombolysis and thrombectomy. Consequently, new adjuvant therapeutic options are urgently needed. MSC ... -
Langzeit-Rezidivrate von paroxysmalem Vorhofflimmern bei Patienten mit akuter zerebraler Ischämie
(2021-10-04)Acute cerebral ischaemia is regarded as the second leading cause of death worldwide and the main cause of longstanding or permanent disability. Atrial fibrillation-associated cerebral ischaemia is related to a high risk ... -
Neural progenitor cell-derived extracellular vesicles enhance blood-brain barrier integrity in stroke mice
(2022-04-28)Objective Extracellular vesicles (EVs) derived from neural progenitor cells (NPCs) enhance post-stroke neurological recovery, albeit the underlying mechanisms remain elusive. Since previous research described an enhanced ... -
Therapeutische Konsequenzen der Echokardiographie bei Patienten mit ischämischem Schlaganfall
(2021-07-27)Diagnostics for the etiological classification of strokes play an important role in the early treatment of this clinical picture. In addition to the prolonged Holter ECG- monitoring, echocardiography is a frequently used ... -
Ultraschall-gesteuerte Freisetzung von an Nanopartikeln gebundenem Nimodipin und deren Anwendung zur Therapie von experimentell erzeugten Vasospasmen an der Chorioallantoismembran des embryonalen Eis
(2022-12-05)Nimodipine prevents cerebral vasospasm and improves functional outcome after aneurysmal subarachnoid hemorrhage (aSAH). The beneficial effect is limited by low oral bioavailability of nimodipine, which resulted in an increasing ... -
Wert des CBV-ASPECTS im Vergleich zum CTA-ASPECTS bei Patienten mit akutem ischämischem Schlaganfall
(2020-11-27)Objectives CTP images analyzed with the Alberta stroke program early CT scale (ASPECTS) have been shown to be optimal predictors of clinical outcome. In this study we compared two biomarkers, the cerebral blood volume ...