Browsing Human- und Zahnmedizin by Referee "Dihazi, Hassan Prof. Dr."
Now showing items 1-13 of 13
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Characterization of urine proteome pattern changes associated with early diabetic nephropathy: a proteomic approach
(2024-04-19)Type 2 diabetes mellitus has become the most common cause of kidney failure in Europe and the United States. In Germany, 8.7 million people live with type 2 diabetes, although an estimated two million more affected people ... -
Analyse von Markerproteinen für Plasmamembran-abgeleitete Mikrovesikel
(2023-07-05)Cells are known to secrete extracellular vesicles (EVs) into their microenvironment. EVs act as mediators of intercellular communication, can travel long distances, and are involved in various ways in the progression and ... -
Proteomische Analyse der Nephrotoxizität im Falle der Cyclosporin A und Tacrolimus Therapie
(2023-05-03)Immunosuppressants have made organ transplantation possible as a therapeutic intervention. One of the first and still most important groups of drugs among immunosuppressants are the calcineurin inhibitors, including ... -
Sezernierte Proteindisulfidisomerase ERp57 als potenziell profibrotischer Faktor in der Nierenschädigung
(2023-04-03)Today many people suffer from chronic kidney diseases (CKD), which often lead to renal fibrosis and kidney failure. For this reason dialysis or renal transplantation often become indispensable to life. There are still ... -
Proteomanalyse parodontaler Zellen in Kultur mit Aggregatibacter actinomycetemcomitans und Eikenella corrodens
(2022-05-12)The periodontium is formed by gingiva, root cementum, PDL and alveolar bone. It is responsible for elastic anchorage of the tooth in the alveolar bone, proprioception during mastication, speech, and protection of adjacent ... -
Untersuchung der Rolle des löslichen E-Cadherins in der Nierenschädigung/-heilung
(2021-04-21)Diabetic nephropathy is a microvascular complication of diabetes mellitus and an important cause of chronic kidney disease. It is characterized by an increased cardiovascular risk and progression to terminal renal failure. ... -
Die Rolle der Proteindisulfidisomerase ERp57 in der Chemoresistenz des Nierenzellkarzinoms
(2019-03-14)It is well-known that renal cell carcinoma is resistant to conventional chemotherapeutic drugs. In the past serious investigation has been made to understand the underlying pathomechanisms. To analyse the mechanism of ... -
Eine Analyse zur Expression detoxifizierender und cytoprotektiver Proteine in der durch Thioacetamid geschädigten Leber der Ratte
(2017-11-01)The understanding of underlying molecular and cellular mechanisms during development of an intrahepatic cholangiocarcinoma (iCC) is far from being complete. Connections of various mutations (APC, DCC, OGG1, p53, k-ras, ... -
Die Prion-Protein-Isoformen
(2016-09-20)We performed two-dimensional immunoblotting of prion protein charge isomers of PrPC from human CSF of CJD patients with sporadic and familial CJD and control patients with distinct codon 129 polymorphism or different prion ... -
Peroxisomes and Kidney Damage
(2014-12-12)This work examined (a) how the endotoxic stress affects peroxisomal function and autophagic degradation of peroxisomes-pexophagy, (b) how a superimposed dysfunction of lysosomes and pexophagy modifies responses to ... -
Proteomische Analyse eines in-vitro-Modells für die interstitielle renale Fibrose: Der osmotische Stress als Fibrose-triggernder Faktor
(2012-07-27)Renal fibrosis (RF) is the final stage of many renal diseases leading to organ function loss. RF is characterised by the deposition and accumulation of extracellular matrix components (ECM). Renal fibroblasts are playing ... -
L-FABP und H-FABP als neue prognostische Biomarker für den Beginn einer Nierenersatztherapie im Falle eines akuten Nierenversagens
(2012-03-08)Acute kidney injury (AKI) has an important meaning in modern medicine. A lot of surveys could demonstrate that acute kidney injury is an independent risk factor for mortality. Despite the ... -
Silikonöl als intraokulärer Medikamententräger
(2010-07-01)PURPOSE Silicone oil (SO) tamponade is basically used as a mechanical tool to keep the retina reattached. It would be also effective, to use SO as a medical treatment of the underlying illness. The purpose of this study ...