Browsing Human- und Zahnmedizin by Referee "Grade, Marian PD Dr."
Now showing items 1-9 of 9
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Auswirkungen einer Variation im TREM-1-Gen auf die Mortalität bei septischen Patienten
(2024-02-12)Sepsis is a life-threatening organ dysfunction caused by a disturbed immune response of the organism to an infectious agent. Sepsis is one of the most common causes of death in intensive care units. Due to its epidemiology ... -
Bedeutung des primären Infektfokus für die Morbidität und Mortalität bei Patienten mit Sepsis
(2017-10-23)a comparison of the outcome of patients with sepsis in view of infection site, especially nosocomial pneumonia, intraabdominal infection and primary bacteremia -
Die Bedeutung des Wnt/β-Catenin-Signalwegs für die Radiotherapieresistenz des Rektumkarzinoms sowie von Normalgewebe am Beispiel von RPE-1-Zellen
(2020-09-22)Colorectal cancer is one of the most common cancers worldwide. The standard treatment for locally advanced rectal cancer is neoadjuvant chemoradiotherapy followed by surgery. However, the response to chemoradiotherapy is ... -
Charakterisierung des NF-κB Signalwegs in Arid1a defizienten Pankreaskarzinomsubtypen
(2021-07-16)Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive, fast proliferating disease with an overall 5-year survival rate of less than 8%. Although therapeutic options have increased within the last years, the extreme ... -
Der Einfluss einer Aktivierung des STAT3-Signalweges auf das Ansprechen kolorektaler Karzinomzellen auf eine Radiochemotherapie
(2019-11-04)CRC is the third most common cancer worldwide. The standard therapy in local advanced rectal cancer is the preoperative radiochemotherapy (RCT) combined with standardized surgery. However, the heterogeneous response to the ... -
Einfluss genetischer Varianten aus dem CTLA-4-Gen auf den Krankheitsverlauf von Patienten mit Sepsis
(2021-08-19)BACKGROUND: The cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is co-inhibitory immune checkpoint protein on the surface of T-cells. It transmits an inhibitory signal in the process of T-cell mediated immune response ... -
Einflüsse und Prädiktoren auf die (Früh-)Kontinenz nach radikaler robotisch-assistierter laparoskopischer Prostatektomie
(2023-08-24)In the cases of locally limited and locally advanced, non-metastatic prostate cancer, surgical removal of the prostate is a primary therapeutic option, which is increasingly performed as robot-assisted laparoscopic radical ... -
Operationsbedürftige abdominelle Shunt-Komplikationen beim kindlichen Hydrozephalus und der Stellenwert einer interdisziplinären chirurgischen Versorgung
(2020-03-23)The following dissertation describes the surgical interventions which where necessary to treat pediatric patients with abdominal complications after insertion of an ventriculo-peritoneal shunt system. Especially the ... -
Prospektive, randomisierte Bewertung des Einsatzes einer stützenden Herrenunterhose nach skrotalen Eingriffen hinsichtlich besserer postoperativer Ergebnisse und gesundheitsbezogener Lebensqualität
(2024-04-26)Background: Elective scrotal surgery is associated with a high rate of postoperative complications. There is no specific recommendation for postoperative care. Aim: We investigated whether support underwear has an impact ...