Browsing Human- und Zahnmedizin by Referee "Hufert, Frank Torsten Prof. Dr."
Now showing items 1-8 of 8
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Etablierung eines T7-RNA-Polymerase basierten Systems zur Generierung von virus-like particles (VLPs) des Oropouche-Virusʼ
(2023-02-21)Oropouche illness is caused by the Orthobunyavirus Oropouche and causes a febrile disease among Middle and South America. The symptoms are e. g. fever, headache and myalgia. Due to infections not just among arthropods but ... -
Charakterisierung der TypI-Interferon-antagonistischen Aktivität der humanpathogenen Orbiviren Tribec-Virus und Kemerovo-Virus
(2015-01-20)Tribec- (TRBV) as well as Kemerovo virus (KEMV) are sheep tick (Ixodes persulcatus and Ixodes ricinus) transmitted Orbiviruses (Reoviridae family). They are under suspicion of causing inflammations of the cerebrospinal ... -
The Role of NS3 Helicase Domain in Hepatitis C Virus Particle Assembly
(2013-11-22)Hepatitis C virus non-structural protein 3 (NS3) is a multifunctional protein that obtains serine protease, RNA helicase and NTPase activities. The enzyme is essential for viral RNA replication. Its protease domain cleaves ... -
Charakterisierung der Eigenschaften der nichtkodierenden Enden der Genomsegmente des Oropouche-Virus und ihre Bedeutung für die virale Transkription/Replikation sowie die Interaktion mit dem Typ-I-Interferonsystem
(2013-07-25)The Oropouche virus (OROV) is a RNA virus from the Bunyaviridae family. Its genome consists of a single-stranded negative sense RNA. The Oropouche fever is caused by this virus and is most common in Central and South ... -
Entwicklung von Rekombinase-Polymerase-Amplifikations-Nachweisverfahren für virale Erreger von Atemwegsinfektionen
(2013-07-19)Objective: Acute respiratory infections (ARI), ranging from the common cold to life threatening Influenza, are frequent causes for medical consultations. Point-of-Care (PoC) diagnosis of Influenza facilitates early antiviral ... -
Inhibition des Interferon-Beta-Systems durch Tribec-Virus
(2013-01-03)The Tribec virus (TRBV) is a tick-transmitted Orbivirus (family Reoviridae) which is suspected to cause neurologic aseptic encephalitis in humans. The activation of the interferon system is the first immune response in ... -
Quantifizierung der Freisetzung bakterieller DNA in Modellen experimenteller bakterieller Meningitis
(2012-10-25)Bacterial meningitis is still a quite severe illness which is associated with local and systemic inflammation and can cause long-term neurological sequelae or death. Common bacteria causing meningitis in Germany are ... -
Entwicklung und Optimierung eines Cytometric Bead Arrays zum Nachweis von afrikanischen hämorrhagischen Fieberviren
(2012-04-23)Viral hemorrhagic fevers (VHF) are acute infections with high infectivity and high case fatality rates. In most of the cases an effective vaccination or causal therapy does not exist or their availability is limited. ...