Browsing Human- und Zahnmedizin by Referee "Metz, Imke PD Dr."
Now showing items 1-5 of 5
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Die axonale Schädigung bei der Multiplen Sklerose: Korrelation von Neurofilament Leichtketten mit histologischen Markern der Axonschädigung und der Klinik
(2023-04-18)Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease associated with axonal injury, and neurofilament light chains in serum (sNfL) are considered a biomarker for this damage. We aimed to investigate the ... -
Apheresis therapy in immunopathologically classified multiple sclerosis patients
(2020-01-31)Plasma exchange and immunoadsorption are second-line apheresis therapies for steroid-unresponsive multiple sclerosis relapses with a variable response rate. The mechanism of action of these therapies is assumed to be the ... -
In-vivo-Untersuchungen der axonalen Degeneration im Tiermodell der Multiplen Sklerose
(2017-12-08)We established a new rat modell for in-vivo research of axonal degeneration in the experimental autoimmune encephalomyelitis (eae). The modell offers to observe the degeneration of single axons in the optic nerv by using ... -
Anatomische Zuordnung tiefer Hirnstrukturen auf hochauflösenden MRT-Aufnahmen fixierter Gehirnproben
(2017-08-02)This thesis is based on formalin-fixed human brain specimens that were scanned on a 3T clinical MR system using a three-dimensional multi-gradient-echo technique (3D-FLASH). The contrast is defined by a combination of ... -
Die Bedeutung der Hedgehog- Signalkaskade in der Tumorgenese von spinalen und kraniellen Chordomen
(2017-07-13)Chordoma is a rare type of cancer that occurs in the bones of the skull base and spine, arising from remnants of embryonic notochord. Although they are slow growing, chordomas are highly recurrent, locally invasive and ...