Browsing Human- und Zahnmedizin by Referee "Moser, Tobias Prof. Dr."
Now showing items 1-6 of 6
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Optogenetic characterization of targeting-optimized Chronos and f-Chrimson variants for auditory encoding in mice
(2024-12-03)Electrical cochlear implants bypass the physiological micromechanics and synaptic sound encoding by sensory hair cells in the cochlea and provide state-of-the-art treatment of sensorineural hearing loss. To overcome the ... -
Hörphysiologische Charakterisierung zweier Mausmodelle mit Schwerhörigkeit
(2021-11-11)In this work, two transgenic mouse models were characterized that showed disruption either of presynaptic Ca2+-influx (CaVβ2) in inner hair cells or of the cochlear K+-cycle (Cx26) by targeted mutagenesis. Approaches of ... -
Altersabhängige Degeneration und Lärmempfindlichkeit des Corti-Organs bei tauben Otof-Knockout-Mäusen
(2015-06-15)Auditory synaptopathies can cause sensorineural hearing loss of varying severity. Causes may be acquired or congenital. DFNB9 is one form of recessive non-syndromal deafness in which a mutation causes disruption of the ... -
Age-dependent changes in the exocytotic efficacy in Kir6.2 ablated mouse pancreatic beta cells
(2014-03-31)ATP-sensitive K+ channels (K -
Electroretinography and exploration of visual and auditory function in mutant mice with synaptic defects
(2012-11-05)At the outset of this work, fundamentals of retinal physiology and electroretinograhy are presented. Scotopic electroretinographic measurements and analyses were performed on two different knockout mouse mutants. One of ... -
Einfluss von Rapamycin auf Myelinmissbildungen in einem Mausmodel einer tomakulösen Neuropathie
(2010-02-05)Tomacula and other forms of focally folded myelin are striking neuropathological features of a diverse group of demyelinating neuropathies, including Charcot-Marie-Tooth (CMT) 4B, CMT4F, CMT1B and hereditary neuropathy ...