Browsing Human- und Zahnmedizin by Referee "Wedekind, Dirk Prof. Dr."
Now showing items 1-13 of 13
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Die Wirksamkeit eines 6-wöchigen hochfrequenten, standardisierten Sportprogramms auf die Erkrankungsschwere in drei Gruppen psychiatrischer Störungen
(2025-04-03)Depression, addiction syndromes and schizophrenia are three of the most common severe psychiatric disorders. For all three disorders, there are established treatment regimes and guidelines for diagnosis and treatment. The ... -
Outcome und Adhärenz moderierende Faktoren einer intensiven Sportintervention in drei psychiatrischen Störungsentitäten: subjektiver Gesundheitszustand, somatoforme Symptomlast, sportliche Vorerfahrung
(2025-02-06)According to the Global Burden of Disease Study 2010, mental illnesses account for 7.4% of the globally lost healthy life years (Whiteford et al. 2015). Identifying and researching effective therapeutic approaches is ... -
Untersuchung plasmabasierter Kompositbiomarker in der Differentialdiagnostik von Alzheimer-Demenz und Vaskulärer Demenz
(2025-01-17)Due to demographic change, dementia is not only at the center of medical research but is also becoming increasingly important in the health economic and social debate. Taking that into consideration, dementia diagnostics ... -
Analyse von Klettersportler*innen
(2025-01-02)With regard to the increasing popularity of climbing, a prospective clinical study was conducted. 51 amateur climbers, who climbed at medium levels of difficulty, were statistically compared with a cohort of 49 non-climbing ... -
Einfluss antiepileptischer Medikamente auf die funktionelle Konnektivität im Routine-EEG bei Patienten mit fokaler nicht-läsioneller Epilepsie
(2024-09-04)Epilepsy is one of the most important neurological disorders and affects up to 1% of the population in Germany (Brandt 2016). It is currently not possible to make a reliable statement on the prognosis and effectiveness of ... -
Bedeutung von Genvarianten im organischen Kationentransporter 1 (OCT1) für Pharmakokinetik, Wirkungen und Nebenwirkungen des Antidepressivums Amitriptylin und dessen Metaboliten Nortriptylin
(2024-07-09)Efficacy and side effects of amitriptyline and nortriptyline vary greatly between patients. Interindividual pharmacokinetic variability may be based on genetic polymorphisms in the drug metabolizing enzymes CYP2C19 and ... -
Inkongruente Bedürfnisbefriedigung bei Suchterkrankten: Ein Vergleich von Menschen mit Alkohol --, Medikamenten und Verhaltenssucht mit gesunden Probanden
(2023-08-22)Both motivational incongruence (INK-G) and depression have been shown to be associated with alcohol dependence and as such a possible target for treatment strategies. Non-substance addictions (NSA) like Internet addiction ... -
Der Effekt einer akuten Sportintervention auf die Stressreaktion bei Patient:innen mit Posttraumatischer Belastungsstörung
(2022-12-14)In this study we investigated the effect of an acute exercise intervention on the stress response of patients with posttraumatic stress disorders, measured with several parameters such as Cortisol for HPA-axis, heart rate ... -
Idiopathisches Parkinson Syndrom und a-Synuclein im Liquor: Bio- und Prognosemarker für Kognition, Krankheitsverlauf und depressive Symptomatik?
(2022-10-18)Bradykinesia, tremor and rigor are the main clinical features by which Parkinson’s Disease (PD) has been diagnosed clinically since the first describer, James Parkinson. A diagnosis-supporting biomarker does not exist yet. ... -
Einfluss der Patientenerwartung auf Wirksamkeit und Verträglichkeit der Elektrokonvulsionstherapie
(2019-06-26)Electroconvulsive therapy (ECT) is the most effective therapy for severe depressive disorders. Though there are known clinical predictors of response (e.g., higher age, presence of psychotic symptoms), there is a lack of ... -
The effect of apomorphine on anodal tDCS-induced cortical plasticity in the human motor cortex
(2018-11-05)The aim of this thesis was to study the effect of apomorphine on non-focal anodal tDCS-induced plasticity and thus further examine the influence of the dopaminergic system on motor cortex plasticity in humans. In a randomized ... -
Psychometrische Evaluation des Fragebogens zum Therapeutenverhalten
(2018-06-08)The great efficacy of psychotherapy was proven repeatedly in the past. As it relies mostly on general factors which all types of treatments have in common, specific factors distinguishing between the different forms of ... -
Psychopharmakologische Behandlung stationärer Patienten mit somatoformen Störungen - Veränderungen über die letzten zwei Jahrzehnte
(2018-02-20)This study aimed at investigating characteristics of the pharmacological treatment of patients with somatoform disorders on the long-term in the interval between 2005 and 2012. Respective variables, before all psychotropic ...