Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Advisor "Knepel, Willhart Prof. Dr."
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Molekulare Mechanismen der Regulation der Glukagon-Gentranskription durch die Pax6-Homöodomäne
(2007-06-05)The peptide hormone glucagon increases glucose output from the liver and thus maintains sufficient blood glucose levels during the fasting state. Malfunctions in biosynthesis and secretion ... -
Bedeutung der Homöodomäne des Transkriptionsfaktors Pax6 für die Aktivierung des Glukagon-Gens durch Pax6
(2004-09-08)Pax6 is one of the essential transcription factors for activating glucagon gene expression and contains two DNA-binding domains, the paired domain and the homeodomain. In vitro, Pax6 binds ... -
Involvement of the paired-domain transcription factor Pax6 in the regulation of glucagon gene transcription by insulin
(2000-11-23)Regulation of gene transcription is an important aspect of insulin's action. However, the mechanisms involved are poorly understood. Insulin inhibits glucagon gene transcription and insulin deficiency is associated ...