Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Advisor "Schu, Peter Prof. Dr."
Now showing items 1-5 of 5
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Etablierung und Analyse von 'knock-out' Mausmodellen der σ1 Untereinheiten des AP 1 Komplexes
(2009-02-10)The multimeric adaptor protein complex 1 (AP-1) is essential for clathrin coated vesicle assembley mediating protein sorting between the trans-Golgi network (TGN) and the endosomal compartment. ... -
Charakterisierung der Eaf 1-Funktion für die Biogenese der Aminopeptidase 1
(2008-11-10)In Saccharomyces cerevisiae the leucine exopeptidase aminopeptidase 1 (Ape1) is synthesized as a cytosolic precursor. After oligomerisation to a homododecameric complex the enzyme gets ... -
σ1-adaptin - the Small Subunit of the Clathrin Adaptor Complex AP-1
(2005-06-03)The adaptor protein AP-1 is a heterotetrameric complex which mediates the formation of clathrin-coated vesicles at the trans-Golgi network and at endosomes. The interactions with ... -
Identification of a new factor essential for vacuolar aminopeptidase I activity.
(2004-12-08)The Saccharomyces cerevisiae vacuolar aminopeptidase I, Ape1p, is transported from the cytoplasm to the vacuole by constitutive autophagocytosis. Ape1p is synthesized as a proform with a ... -
Role of Adaptor Proteins in MPR sorting
(2003-06-04)Mannose 6-phosphate receptors mediate sorting of lysosomal enzymes and thus play an important role in lysosomal biogenesis. They bind to the mannose 6-phosphate residues on the lysosomal ...