Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Referee "Kessel, Michael Prof. Dr."

Different inter-domain linker regions regulate the binding of UHRF1 and NP95 to histone H3

Tauber, Maria (2017-06-15)

Ubiquitin-like with PHD and RING Finger domains 1 (UHRF1 in human, NP95 in mouse) is an important epigenetic regulator connected to apoptosis and tumor development. UHRF1/NP95 integrates different chromatin modifications ...

Characterization of chondrogenic progenitor cells using mass spectrometry and multidimensional separation approaches

Atanassov, Ilian (2015-07-03)

Modern day mass spectrometry (MS) has evolved into a powerful analytical technique, central to the field of proteomics. Currently, the identification and quantification of proteins from different biological samples can be ...

Identifizierung neuer Coregulatoren von SOX9 und RUNX2 in chondrogenen Progenitorzellen in der Osteoarthrose

Cingöz, Gökhan (2015-06-23)

Osteoarthritis is a degenerative disease of the joints. It is characterized by a successive destruction of the articular cartilage and surrounding structures. Osteoarthritis is the most common musculoskeletal joint disease ...

Functional Analysis of Two Major Sperm Tail Proteins Identifies ODF1 as Being Essential for the Tight Linkage of the Sperm Head to the Tail via SPAG4 and ODF2 as A Component of the β-catenin Destruction Complex

Yang, Kefei (2015-04-02)

In the mammalian sperm tail, the outer dense fibers (ODFs) are accessory fibers accompanying the axonemal tubuli doublets on their outer site. The ODFs are composed of at least 14 polypeptides of which only a few have been ...

In situ and in vitro analysis of germ and stem cell marker-positive cells in the postnatal ovary of the common marmoset monkey (Callithrix jacchus)

Fereydouni, Bentolhoda (2014-07-25)

Oogonia are the proliferating diploid germ cells within the female gonad giving rise to oocytes. Oocytes are the meiotic female germ cell stages. In humans, almost all oogonia enter meiosis between weeks 9 and 22 of prenatal ...

Human and mouse meniscus progenitor cells and their role in meniscus tissue regeneration

Muhammad, Hayat (2014-05-19)

Osteoarthritis (OA) is a degenerative disease of hyaline cartilage. The cartilage is an avascular tissue, once damaged it is difficult to repair. Articular cartilage is responsible for the smooth, frictionless, and painless ...

miRNA functions in pluripotency and spermatogenesis

Smorag, Lukasz (2013-10-23)

For quite a long time, non-coding RNAs (ncRNAs) were discriminated and considered as an evolutionary error. In light of this opinion, discovery of small ncRNAs, in particular microRNA (miRNA), which can regulate the gene ...

Reconstruction of late Quaternary landscape dynamics in the Podocarpus National Park region southern Andes of Ecuador

Rodríguez, Fernando (2013-05-13)

The Ecuadorian Andes harbor ecosystems with the highest biodiversity on earth. Background information on past environmental dynamic is needed to understand, conserve and manage the ecosystems and their biodiversity. Three ...

Association of killer immunoglobulin-like receptor genes with viral loads in experimental SIV infection of rhesus macaques (Macaca mulatta)

Albrecht, Christina (2013-01-09)

Multiple epidemiological studies in human demonstrated associations between KIR/MHC class I gene combinations and HIV-1 disease progression, implicating important roles of KIR-expressing NK cells in defencing HIV. The ...

The influence of post-translational modifications on biology of the linker histone HIS-24 in Caenorhabditis elegans

Studencka, Maja (2012-06-26)

In the eukaryotic nucleus the genome is packaged into a nucleoprotein complex known as chromatin. The chromatin is composed of DNA, core histones (H2A, H2B, H3, H4), linker histones (H1) as well as non-histone proteins. ...

Cellular Prion Protein (PrPC): Identification and Characterization of Novel Interacting Partners

Zafar, Saima (2011-12-07)

The cellular prion protein (PrPC) is highly conserved throughout the evolution of mammals. (What does this sentence mean? What do you mean by ``conserved´´? This protein was higly conserved ...

Effekte der Klasse-3 Semaphorine auf die Entwicklung und Progression maligner Hirntumoren

Bode, Julia (2011-03-25)

The neuropilins are endothelial cell surface receptors that function as receptors for the angiogenic factors of the vascular endothelial growth factor (VEGF) family. They also function as ...

UPSTREAM PATHWAYS REGULATING ERYTHROPOIETIN GENE EXPRESSION IN THE LIVER DURING ACUTE PHASE RESPONSE: A CENTRAL ROLE FOR IL-6.

Ramadori, Pierluigi (2010-08-18)

The acute phase response is the systemic reaction of an organism to insults like infection, trauma, or burning and it represents the first line of defense of the body to tissue-damaging ...

Functional Characterization of the Histone Methyltransferase and Methyl DNA Binding Protein MDU and its Role in Epigenetic Regulation of Rbf Gene in Drosophila Melanogaster

Gou, Dawei (2008-12-16)

The methylation of genomic DNA and histones is paramount for the execution of epigenetic events such as imprinting, gene dosage compensation, and gene silencing. Studies in fungi, plants ...