Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Referee "Thumm, Michael Prof. Dr."
Now showing items 1-8 of 8
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HORMA domain proteins in Autophagy initiation
(2022-08-01)The autophagic pathway is an evolutionarily conserved strategy among eukaryotic cells for maintaining cell homeostasis at the basal level and during stressful conditions. It removes protein aggregates, damaged organelles, ... -
The interplay of SmNBR1 and SmATG8 in selective autophagy of the filamentous fungus Sordaria macrospora
(2018-03-19)Autophagy is a conserved ubiquitous degradation process in eukaryotic cells which is mainly investigated in the baker´s yeast Saccharomyces cerevisiae. It includes the random sequestration of defective and excessive proteins ... -
Structural characterization of autophagy related protein complexes
(2017-06-08)Autophagy is a conserved and highly regulated process in eukaryotic cells that plays an important role in maintaining cellular homeostasis. During macroautophagy a double membrane grows de novo that encloses cytoplasmic ... -
α-synuclein in Saccharomyces cerevisiae: model for aggregate clearance, cell survival and influence of autophagy
(2012-06-26)α-synuclein is a neuronal protein involved in several neurodegenerative disorders, including Parkinson's Disease (PD). Misfolding and accumulation of α-synuclein into cytoplasmic inclusions correlate with the pathogenesis ... -
Structural and functional characterization of the autophagy proteins Atg5 and Atg16L1 and their interaction partners
(2011-05-26)Autophagy is a degradative pathway conserved in eukaryotes. During autophagy a portion of the cytoplasm is sequestered by a de novo forming isolation membrane resulting in the formation of ... -
The production of VLCPUFAs in plants
(2011-03-17)Very long-chain polyunsaturated fatty acids (VLCPUFAs) like eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA) are health-beneficial components in the human diet. However, due to ... -
Investigation of early endosomal sorting and budding
(2009-11-04)Early endosomes constitute a major sorting platform of eukaryotic cells. They receive endocytic carrier vesicles from the plasma membrane and trafficking vesicles from the Golgi complex and ... -
Molecular analysis of vesicle biogenesis during autophagy
(2009-05-14)Autophagy in Saccharomyces cerevisiae comprises diverse processes that transport cytoplasm and even organelles into the vacuolar lumen for degradation. During macroautophagy out of the pre- ...