Fakultät für Biologie und Psychologie (inkl. GAUSS): Recent submissions
Now showing items 1-20 of 1708
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Functional relevance of oligodendroglial CDC42 effector proteins CDC42EP1 and CDC42EP2 in myelin morphogenesis
(2025-11-12)Myelin sheaths are composed of multiple compacted membrane layers that tightly encase the underlying axon. Structural abnormalities of myelin indicate pathological processes and are frequently associated with neurological ... -
Computational analysis of nucleosome assembly and cis-regulatory DNA elements
(2025-11-12)Induced pluripotent stem cells (iPSCs) represent embryonic stem cells (ESCs) that are reprogrammed from somatic stem cells. iPSCs can be directed to differentiate into any cell type in the human body, therefore, holding ... -
Comparative Cognitive Flexibility Assessment: Multidimensional set-shifting in monkeys, adult humans and children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD)
(2025-11-10)This thesis aims to provide a be0er and more comprehensive understanding of one of the crucial execu8ve func8ons: cogni8ve flexibility (Chapters 2 and 3). To that end, we have developed a novel mul8-dimensional set-shiEing ... -
Optimierung der Diagnostik von der Posttraumatischen Belastungsstörung und der komplexen Posttraumatischen Belastungsstörung nach ICD-11
(2025-10-30)The establishment of the diagnosis of complex post-traumatic stress disorder (cPTSD) in the new classification system (ICD-11) has brought with it new diagnostic procedures. However, these procedures do not differentiate ... -
Role of bacterial rhamnolipids in plant tolerance to abiotic stresses
(2025-10-29)Rhamnolipids (RLs), glycolipids produced by Pseudomonas and Burkholderia species, have been described as potential biocontrol agents due to their antagonistic activity against pathogens and their ability to induce plant ... -
Bringing bioinformatics to the bench: SubtiWiki 5.0 and new web tools for research
(2025-10-29)Model organisms are central to biological research, as their study provides crucial insights into fundamental processes of life and enables biotechnological applications. The intensive research on these organisms spans ... -
Complex Coacervation of Disordered Proteins: focus on α-Synuclein and Polyamines
(2025-10-28)The discovery of phase-separated bodies in cells has revealed an additional mesoscale layer of organisation in cellular and molecular biology. The enrichment of RNA in these biomolecular condensates suggests that charge ... -
Addressing Habits in Anorexia Nervosa
(2025-10-23)Anorexia Nervosa (AN) is a mental disorder that affects up to 0.3% of men and 6.2% of women worldwide and places a significant burden on the individual, their social environment and the healthcare system. Although ... -
Studies on Testicular Development and Aging in the Common Marmoset (Callithrix jacchus) and the Establishment of Somatic Testicular Cell Lines
(2025-10-15)The phenomenon of reproductive ageing in women has been known for a long time and some aspects of this phenomenon are well understood. However, ageing effects in the testes were not recognized for a long time, as aged males ... -
Design-based Research on Promoting Relevance Perceptions in Socioscientific Teaching and Learning – Sustainable Oil Palm Cultivation in Science Teacher and Forestry Education
(2025-10-02)Recent interdisciplinary scientific research has suggested evidence-based management strategies for more sustainable oil palm cultivation, such as reducing agrochemicals and establishing agroforestry systems. For this ... -
The evolution of an unusual adult sex ratio in wild redfronted lemurs (Eulemur rufifrons)
(2025-09-19)Variation in adult sex ratios (ASR), defined as the proportion of adult males to females, reflects complex demographic and evolutionary processes. Female-biased ASRs characterize the vast majority of non-monogamous mammals, ... -
Investigations towards a link of morphodynamics and transcriptional pattern in embryonic tissues during morphogenesis
(2025-09-16)The acquisition and loss of epithelial characteristics—such as apico-basal polarity, cell–cell adhesion, and barrier integrity—are essential processes during development, regeneration, and disease. While epithelial–mesenchymal ... -
Advancing soil nematode research: molecular, morphological and stable isotope analyses
(2025-09-16)The overarching aim of this dissertation was to explore the impact of environmental variances on soil nematode communities, their trophic interactions and their ecological roles by integrating traditional morphological ... -
Psychological Effects of Age and Hormonal Contraceptive Use in the Context of Female Reproductive Decision Making
(2025-09-05)Reproductive decision making is a central aspect of human life, shaped by both biological and psychological factors. While prior research has often focused on fertility-related outcomes, little is known about if and how ... -
Female fitness in wild Assamese macaques (Macaca assamensis)
(2025-09-03)Variation in fitness arises from the interaction of life-history constraints and social and environmental variability. In long-lived, slow-reproducing species like primates, selective pressure on fitness components ... -
Molecular mechanisms underlying silent synapse generation and their role in drug-associated behaviors
(2025-08-29)Silent synapses are immature glutamatergic connections that express stable NMDARs, while AMPARs are absent. These synapses are abundant during early development and serve as plasticity substrates, offering synaptic ... -
Multi-omics analysis of human transcription elongation factors
(2025-08-19)Transcription by RNA Polymerases (Pol) is a highly regulated fundamental process in all living organisms, with its misregulation linked to various diseases, developmental issues, and aging. This intricate process is ... -
Children’s Identification and Filling of Knowledge Gaps in Digital Learning Environments
(2025-08-11)Children face uncertainty during learning, which can indicate they have a gap in their knowledge. Identifying and addressing knowledge gaps is fundamental for effective learning. Metacognition and external feedback play a ... -
Analysis of small nucleolar (sno)RNA shuttling in Saccharomyces cerevisiae
(2025-08-07)Small nucleolar (sno)RNAs are a group of non-coding RNAs and can be classified into box C/D snoRNA and box H/ACA snoRNA based on their conserved sequences. They are further associated with snoRNA core proteins to form ... -
Analysis of Transcription Factor Binding and Cancer Stage-Specific Regulatory Dynamics Using DNA-Binding Domain Annotations
(2025-07-31)Transcription Factors (TFs) regulate gene expression by binding to specific DNA sequences through their DNA-Binding Domain (DBD)s. Accurate modeling of TF–DNA interactions is essential for uncovering the mechanisms of ...