Dokumente Fakultät für Chemie (inkl. GAUSS) nach Gutachter "John, Michael Dr."
Anzeige 21-36 von 36
-
New Synthetic Analogues for Biological Fe/S Clusters
(2023-03-20)Iron-sulfur (Fe/S) clusters are omnipresent and are essential components in virtually all life forms due to their versatile structures and functions. Biological systems extensively employ Fe/S clusters, especially with ... -
Resource-Economical C–H Activation for Late-Stage Functionalization
(2021-07-07)Organic synthesis has traditionally relied on step-, time- and resource-intensive strategies, namely the functional group interconversion and, more recently, on cross-coupling reactions. These approaches have enabled the ... -
Resource-Economical Synthesis by Selective Metal-Catalyzed C–H Activations
(2021-04-30)The advent of new synthetic strategies has enriched the synthetic organic chemistry to access molecules with tremendous complexity. In this context, transition metal-catalyzed C−H activation has emerged as a powerful tool ... -
Selective C–H Activation by Ruthenium(II) Carboxylate and Nickelaelectro-Catalysis
(2021-01-28)This doctoral thesis was divided into two main parts. In the first part, ruthenium(II)-catalyzed ortho-C–H alkynylations of diverse benzoic acids were achieved for the synthesis of aromatic alkynes. And meta-C–H activations, ... -
Site-Selectivity in Ruthenium-Catalyzed C–H and C–C Activations
(2020-09-23)During the past decades, transition metal-catalyzed C–H and C–C activation has been recognized as a powerful platform in organic synthesis to access the selective construction of new C–C and C–Het bonds. The full control ... -
Sustainable Methods in C–H Functionalizations
(2023-05-30)Cross-coupling chemistry has matured in an attractive tool in synthetic organic chemistry to realized efficient formation of C‒C and C‒Het bonds. However, these transformations are also associated with certain drawbacks, ... -
Sustainable Synthesis by 3d Transition Metal Electro-Catalyzed C─H Activation
(2020-01-20)During the last years, new opportunities are represented by the development of 3d transition metal-catalyzed C–H activation, with possible benefits due to the significantly lower toxicity, high natural abundance and ... -
Synthesis of Modified Biomolecules to Investigate Neuronal Processes
(2021-04-30)Action potentials are an essential process for signal transmission in excitable cells. At chemical synapses, the action potential triggers the release of neurotransmitters from synaptic vesicles to transmit the signal to ... -
Synthesis of Orotidine-5'-monophosphate modifications for the study of the catalytic activity of the enzyme Orotidine-5'-monophosphate decarboxylase
(2022-01-27)In this thesis, the synthesis of OMPD substrate analogs was investigated to further elucidate the mechanism of the OMPD. As inhibiting molecules, 6-thioamido UMP, OMP methyl ester, reduced OMP, and nonpolar substituted ... -
Synthesis of rare nucleobases and artificial nucleotides for investigation of catalytic enzyme activity
(2019-10-25)Enzymes are involved in replication, transcription and translation of DNA, as well as the synthesis of nucleobases. The roles and mechanisms for many of these enzymes stay broadly unknown until today. The herein presented ... -
Tailoring and Exploiting Magnetic Anisotropy in Low Coordinate 3d Transition Metal Complexes.
(2023-07-04)Among 3d transition metal based SMMs, Co(II) SMMs is the most-studied group owning to the high-spin electronic configuration (CoII, d7) which yields second-order spin-orbit coupling or even first-order spin-orbit coupling. ... -
Towards a total synthesis of bazzanin K
(2022-05-31)Bazzanin K is a natural product from the group of macrocyclic bis-bibenzyls which was isolated from the liverwort bazzania trilobata. This work is dedicated towards the development of a synthetic strategy with bazzanin K ... -
Transformations of Energy-Related Small Molecules at Dinuclear Complexes
(2021-02-05)The urgent need for the development of carbon-neutral energy conversion schemes has inspired chemists worldwide to investigate catalytic water splitting using sunlight as the energy source. A key component for the preparation ... -
Transition Metal- and Electro-Catalyzed C-H and B-H Activation for the Efficient Synthesis of Carborane Derivatives
(2023-01-12)The emergence and rapid development of transition metal-and electro-catalyzed C-H activation has proven to be a powerful tool in the assembly of complex molecular structures. in addition, the selective synthesis of carborane ... -
Transition Metal-Free Catalytic Systems for the Utilization of CO2 to Achieve Valuable Chemicals
(2020-11-03)The utilization of one of the most threatening greenhouse gases regarding the climate change could help changing its reputation from a harmful waste toward a green alternative feedstock. For the afore-mentioned reason, it ... -
Visible Light-Mediated Metal-Free Photocatalytic Oxidative Reactions and Cycloadditions
(2020-11-16)Currently, there is a strong demand for the development of sustainable chemistry by reducing hazardous substances and using less energy during the process. Hence, ‘Green Chemistry’ or ‘Sustainable Chemistry’ has become the ...