Dokumente Fakultät für Chemie (inkl. GAUSS) nach Gutachter "Koszinowski, Konrad Prof. Dr."
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Entwicklung regio- und enantioselektiver Transformationen an Alkenen mittels λ3-Iodan-Reagenzien bzw. chiraler Selen-π-Säure-Katalysatoren
(2020-09-02)In this thesis three novel oxidative functionalisations of alkenes are presented. The focus lay on the one hand on the development of the first aerobic phosphatation of alkens using a dual selenium-pi-acid-photoredox ... -
Estimating Molecular Weights of Organometallics in Solution with Diffusion NMR Techniques
(2017-03-31)This PhD thesis focuses on diffusion NMR spectroscopy and the utilisation of the external calibration curve (ECC) diffusion-ordered spectroscopy (DOSY) technique on the estimation of molecular weights of organometallic ... -
Experimental and Computational Studies on Ruthenium- and Manganese-Catalyzed C-H and C-C Activation
(2019-11-07)During the last years, transition metal-catalyzed C–H and C–C activation has emerged as a powerful tool for the selective construction of C–C and C–Het bonds. In this context, a detailed mechanistic understanding of these ... -
From Copper to Gold: Identification and Characterization of Coinage-Metal Ate Complexes by ESI Mass Spectrometry and Gas-Phase Fragmentation Experiments
(2020-01-09)Organocuprates are important reagents with numerous applications in preparative organic chemistry, which has led to extensive investigations regarding their molecular composition. However, while lithium organocuprates have ... -
Funktionelle Polymere mittels kontrollierter Polymerisationstechniken: Von der Massenspektrometrie endfunktionalisierter Polymere und den mechanischen Eigenschaften photovernetzbarer Blockcopolymere
(2019-02-06)In this thesis polymers were functionalized with terminal ammonium groups leading to new fields of their application. Their analysis by mass spectrometry was optimized or became generally accessible. In addition, reversibly ... -
Homogeneous and Heterogeneous Chelation-Assisted Ruthenium(II)-Catalyzed C–H Functionalizations
(2017-01-03)Ruthenium(II)-catalyzed direct C–H functionalizations have emerged as a powerful tool for organic chemists to construct C–C and C–Het bonds. In order to rationally improve the efficiency of these methods a mechanistic ... -
Implementing Ion Imaging to Probe Chemical Kinetics and Dynamics at Surfaces
(2018-07-03)In this thesis I present a novel surface science apparatus and new methods to measure and analyze reaction kinetics at surfaces. By combining crossed-beam surface scattering with universal fs-laser ionization and ion ... -
Ion mobility mass spectrometry as a powerful tool to analyze complex macromolecular systems
(2021-02-01)Modern applications of polymers rely on intricately tailored macromolecules exhibiting very specific properties and therefore require extensive analysis. In this context, IMMS is an immensely powerful technique since it ... -
Late-Stage Peptide Diversification via Transition Metal-Catalyzed C─H Activation
(2020-10-13)The late-stage modification of peptide is of great value to drug discovery and medicinal chemistry. Metal catalyzed C─H activation has emerged as efficient and step-economic strategy for post-translational peptide engineering. ... -
Merging Electrosynthesis with 3d Transition Metal-Catalyzed C–H Transformations
(2021-07-12)In recent years, oxidative C–H transformations have emerged as increasingly powerful tools in molecular syntheses. However, despite great progress towards more atom and step economic synthetic methods, oxidative couplings ... -
Metal-induced aggregation of ß-peptides on membrane surfaces
(2022-04-05)According to the liquid mosaic model of Singer and Nicolson, the cell membrane defines the boundaries of a cell to the inside and outside and describes a twodimensional lipid bilayer. Integrated into this lipid bilayer ... -
Mikroskopische Reaktivität Metallorganischer Spezies
(2023-03-15)In oder to better understand cross-coupling reactions, the oxidative addition between organo halides and organometallates based on iron, cobalt and copper was investigated by using ion-molecule reactions in the gas phase. ... -
Nickel-Catalyzed Secondary Alkylations and Fluoroalkylations via C–H Activation
(2016-07-15)In the past several decades, transition metal-catalyzed cross-coupling reactions proved to be of utmost importance within organic synthesis. However, required prefunctionalization of substrates remained as a major disadvantage ... -
Novel Cationic Sulfur Reagents and their Application in Electrophilic Group-Transfer Reactions
(2020-06-08)The two major research achievements of this work are the development of novel sulfur-based electrophilic transfer reagents based on pyridinium, as well as the extension of the reactivity of already established imidazolium ... -
Organoferrate als Intermediate in Eisen-Katalysierten Kreuzkupplungsreaktionen
(2019-05-24)In the context of this work a combination of ESI mass spectrometry, mößbauer spectroscopy and electrical conductometry was used to identify and characterize a large number of organoferrates. These anionic species, which ... -
Resource-Economical C–H Activation for Late-Stage Functionalization
(2021-07-07)Organic synthesis has traditionally relied on step-, time- and resource-intensive strategies, namely the functional group interconversion and, more recently, on cross-coupling reactions. These approaches have enabled the ... -
Ruthenium(II)-Catalyzed C-N, C-O and C-C Formations by C-H Activation
(2017-02-16)Ruthenium catalyzed C-N, C-O and C-C formation is achieved by C-H activation. access to primary aminoketones leds to synthetic synthons for different heterocycles. removable and reusability was shown first time in C-O bond ... -
Ruthenium- and Cobalt-Catalyzed Chelation-Assisted C-H Functionalizations
(2015-07-09)Ruthenium- and cobalt-catalyzed C-H activations have been discribed in this thesis, which provided expedient routes to the synthesis of synthetically useful compounds. Moreover, detailed mechanistic studies were also ... -
Schwingungsspektroskopische Untersuchungen zur Chiralitätserkennung und Torsionsdynamik bei Alkoholen
(2020-10-20)In this thesis different implications of molecular chirality are explored by experimental and quantum chemical methods. Discriminating interactions between molecules of different handedness, termed chirality recognition, ... -
Site-Selectivity in Ruthenium-Catalyzed C–H and C–C Activations
(2020-09-23)During the past decades, transition metal-catalyzed C–H and C–C activation has been recognized as a powerful platform in organic synthesis to access the selective construction of new C–C and C–Het bonds. The full control ...