Browsing Naturwissenschaften, Mathematik und Informatik by Referee "Faesen, Alex Dr."
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Proteogenomic peptide discovery in large search spaces
(2025-01-30)Novel peptide and protein discovery is of therapeutical relevance and ignited the development of methods for their identification, commonly done via mass spectrometry. The latter relies on a well-characterised proteogenomic ... -
Macromolecules in Motion by High-resolution Cryo-EM
(2024-05-06)Protein synthesis, the translation of the genetic code into a defined sequence of amino acids, is a central, highly dynamic and regulated step in gene expression. The well-defined bacterial translation system enables to ... -
Investigation on the molecular factors driving the formation of distinct tau 'strains'
(2022-11-28)Pathological aggregation of the microtubule-binding protein tau into amyloid fibrils is a hallmark of different neurodegenerative diseases collectively termed tauopathies. To date, tau amyloid structures associated with ...