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    • Proteogenomic peptide discovery in large search spaces 

      Horokhovskyi, Yehor (2025-01-30)
      Novel peptide and protein discovery is of therapeutical relevance and ignited the development of methods for their identification, commonly done via mass spectrometry. The latter relies on a well-characterised proteogenomic ...
    • Macromolecules in Motion by High-resolution Cryo-EM 

      Petrychenko, Valentyn (2024-05-06)
      Protein synthesis, the translation of the genetic code into a defined sequence of amino acids, is a central, highly dynamic and regulated step in gene expression. The well-defined bacterial translation system enables to ...
    • Investigation on the molecular factors driving the formation of distinct tau 'strains' 

      Chakraborty, Pijush (2022-11-28)
      Pathological aggregation of the microtubule-binding protein tau into amyloid fibrils is a hallmark of different neurodegenerative diseases collectively termed tauopathies. To date, tau amyloid structures associated with ...