| dc.contributor.advisor | Alim, Karen Dr. | |
| dc.contributor.author | Bäuerle, Felix Kaspar | |
| dc.date.accessioned | 2019-12-20T09:48:42Z | |
| dc.date.available | 2019-12-20T09:48:42Z | |
| dc.date.issued | 2019-12-20 | |
| dc.identifier.uri | http://hdl.handle.net/21.11130/00-1735-0000-0005-12DC-F | |
| dc.identifier.uri | http://dx.doi.org/10.53846/goediss-7786 | |
| dc.language.iso | eng | de |
| dc.relation.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.subject.ddc | 571.4 | de |
| dc.title | On mass transport in Physarum polycephalum | de |
| dc.type | doctoralThesis | de |
| dc.contributor.referee | Alim, Karen Dr. | |
| dc.date.examination | 2019-06-07 | |
| dc.description.abstracteng | The network-forming slime mold Physarum polycephalum has proven to
be the epitome of self-organization. As a single cell it adapts seemingly
intelligent to stimuli, integrating various inputs to create a coordinated
response over an extended body plan in space and time. Most feats performed
by Physarum polycephalum are linked to its morphology which is
constantly reforming by transporting mass from pruning parts to growing
ones. Cytoplasmic ows, the means for mass transport, are directly linked
to periodic contraction patterns. Here I investigate induced mass transport
in slime molds via two complementary methods: Firstly, I follow the reorganization
of Physarum polycephalum networks after severe wounding and
secondly I present that modulating the phase di erence between harmonics
increases the pumping e ciency in the slime mold when subjected to
blue light.
Spatial mapping of the contraction changes in response to wounding
reveal a multi-step pattern. Phases of increased activity alternate with
cessation of contractions and stalling of ows, giving rise to coordinated
transport and growth at the severing site. Overall, severing surprisingly
acts like an attractive stimulus enabling healing of severed tubes. Furthermore
I show that a modulation of the phase di erence between harmonics,
given cost-free constraints, directly in uences the pumping e ciency by
adjusting the pumps maximal occlusion. I nd that the slime mold adapts
its waveform accordingly when evacuating an area. It can thereby react to
its environment in a self-organized fashion without changing its energy
demand.
Wounding is a severe impairment of function, especially for an exposed
organism like the network-forming true slime mould Physarum polycephalum
and wavelike patterns driving transport are ubiquitous in living
systems. The presented results may open up new venues to investigate the
biochemical wiring underlying P. polycephalum’s complex behaviours, provide
a novel metric for wavelike patterns in general and demonstrate the
crucial role of nonlinearities in living systems. | de |
| dc.contributor.coReferee | Bodenschatz, Eberhard Prof. Dr. | |
| dc.subject.eng | Biophysics | de |
| dc.subject.eng | Biofluidics | de |
| dc.subject.eng | Fluid dynamics | de |
| dc.subject.eng | Wave patterns | de |
| dc.subject.eng | Peristalsis | de |
| dc.subject.eng | Physarum polycephalum | de |
| dc.identifier.urn | urn:nbn:de:gbv:7-21.11130/00-1735-0000-0005-12DC-F-4 | |
| dc.affiliation.institute | Göttinger Graduiertenschule für Neurowissenschaften, Biophysik und molekulare Biowissenschaften (GGNB) | de |
| dc.subject.gokfull | Biologie (PPN619462639) | de |
| dc.identifier.ppn | 1686307500 | |